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Biomedical subjects

F Bauwens

Publications and source records attributed to F Bauwens.

7 recordsLinked to original sources

Blood pressure load determines left ventricular mass in essential hypertension.

In a series of 35 newly diagnosed, previously untreated patients (mean age 46 years) with mild to moderate essential hypertension, office blood pressure measurements, 24-hour ambulatory blood pressure monitoring, and determination of left ventricular mass index by echocardiography according to the formula of Devereux were performed. We aimed at correlating left ventricular mass index with systolic and diastolic office blood pressure, mean 24-hour systolic and mean 24-hour diastolic blood pressure, systolic and diastolic load. Left ventricular mass index did not correlate with office systolic and office diastolic blood pressure. On the contrary, all correlations with ambulatory blood pressure parameters and left ventricular mass index turned out to be significant (mean 24-hour systolic blood pressure: r = 0.344, P = 0.026; systolic load: r = 0.408, P = 0.020; mean 24-hour diastolic blood pressure: r = 0.490, P = 0.004; diastolic load: r = 0.504, P = 0.003). These results clearly demonstrate that ambulatory blood pressure determinants but not the office blood pressure parameters are well correlated with left ventricular mass index in mild to moderate essential hypertension. Blood pressure load is as important as mean 24-hour blood pressure in this regard.

Adult

Attributional style and depression: a controlled comparison of remitted unipolar and bipolar patients.

Attributional style was investigated in remitted affective disorder patients (23 unipolars and 26 bipolars) and 26 non-psychiatric controls. We found a specific cognitive vulnerability in unipolars. Unipolars attributed negative events to causes that were more stable--but not more internal nor more global--than bipolars and controls, and did not attach more importance to these events. Attributional vulnerability seemed more apparent in patients with longer histories of depression.

Adult

Social adjustment of remitted bipolar and unipolar out-patients. A comparison with age- and sex-matched controls.

Various areas of social adjustment were compared using the Social Adjustment Scale in 27 remitted bipolars, 24 remitted unipolars and 25 normal controls matched for age and sex. Scores for global adjustment and for social and leisure activities were significantly worse in patients than in controls. The maladjustment in social and leisure activities appeared only in 'contact with friends' for bipolar patients and 'diminished social interactions' for unipolar patients. Unipolar patients differed significantly from controls on the items investigating sexual adjustment. In unipolars, social maladjustment seemed to be independent of the course of the disease; in bipolars, it was partly related to the mean number of lifetime episodes and current residual symptoms.

Activities of Daily Living

Isolated rheumatic carditis, a disease in search of diagnostic criteria.

We report a case of acute dilated cardiomyopathy with histologic proof of inflammatory myocarditis. Although immunosuppressive therapy seemed to induce the resolution of the inflammatory infiltrate, it had no effect on the clinical course. The diagnosis of isolated rheumatic carditis was considered because of the finding of a very high antistreptolysin O titre and lack of evidence for either viral disease, infection with group C and G streptococci or other causes of spuriously high titres of anti-streptolysin O. In view of our conclusion longterm chemoprophylaxis was instituted.

Adult

Relapsing digital ulcers.

A 72-years-old male patient is described who presented with relapsing, digital ulcers on both feet, accompanied by digital cyanosis ("purple toes"). All episodes occurred 5 months after starting coumarin treatment for chronic atrial fibrillation and low output failure. Massive mural thrombosis was discovered of the entire abdominal aorta. Because of the clinical picture, together with progressive renal failure and persistent eosinophilia, cholesterol embolization from an ulcerated atherosclerotic plaque within the mural thrombus was highly suspected. Besides the clinical presentation of our patient, the spectrum of cholesterol embolization is much wider. The role of coumarin therapy is still speculative. Numerous reports however, indicate a potential role in precipitating the syndrome. The only therapy available consists of removing the source whenever possible.

Aged

Localisation and risk factors of peripheral arterial occlusive disease in the female.

Peripheral arterial occlusive disease has been described frequently as a disease affecting predominantly men. There is only a few information available concerning peripheral vascular disease in the female. Therefore, the aim of the present study was to examine risk factors in relation to localisation and symptoms of peripheral arterial occlusive disease in female patients. A retrospective study has been performed in 48 female patients (52-82 years with a mean age 69.5 years). Finally 45 patients were witheld because they had all a doppler examination and an oscillography of the lower limbs. The majority of the patients, namely 22 patients (49%) had combined ileofemoral and distal lesions. There were 15 patients (33%) who had isolated distal lesions, while only 8 patients (18%) had isolated ileofemoral vascular lesions. With respect to the symptoms the population could be divided in three groups: 16 patients (36%) were asymptomatic, 19 patients (42%) had intermittent claudication and 10 patients (22%) had rest pain and necrosis. Smoking was not the predominant risk factor in this group. Diabetes mellitus seemed to enhance distal vascular lesions, while arterial hypertension, obesity and lipids were predictive risk factors in peripheral vascular disease in the female. A high incidence of cardiovascular disease (31 patients, 69%) and cerebrovascular disease (13 patients, 29%) was concomitant.

Aged