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Biomedical subjects

F Behrens

Publications and source records attributed to F Behrens.

At least 37 records · Page 2Linked to original sources
PubMed1984

Basic concepts and applications in open tibial fractures.

These data indicate that unilateral frames erected with rather stiff pins and rods carry few of the serious problems that were typical for the traditional half frames characterized by weak components, routine medial application, and limited pin spread. In comparison with one- and two-plane bilateral fixator configurations, unilateral frames are safer and more versatile, provide better access to limb and injury, do not interfere with knee and ankle motion, facilitate patient mobility, allow full unsupported weight bearing, and have a low rate of serious complications. While the successful and effective use of unilateral half frames is predicated on the use of relatively stiff components, they can be erected with most presently available devices. If a modular fixator is employed, long clamps, which allow for an extended pin spread, are desirable. The routine use of partial and full weight bearing increases patient comfort and mobility and may have beneficial effects on the healing process. In order to have the fracture site accept larger loads toward the end of the treatment period, we have recently started to sequentially decrease the rigidity of our fixator frames by moving the longitudinal rods further away from the tibia and selectively loosening the two clamps closest to the fracture site. This allows for the transmission of almost all compressive and transverse bending loads across the fracture site but provides considerable protection from sagittal bending moments, which often cause anterior bowing late in the healing period.

Adolescent↗
PubMed1983

Bladder problems in pelvic injuries treated with external fixator and direct urethral drainage.

In the treatment of unstable pelvic fractures, external fixators provide the advantages of substantial pain relief, easier nursing care, early mobilization, decreased hospital stay, and direct access to open wounds. Urethral catheter drainage alone for ruptured bladders obviates the need for open surgical repair in a critically injured patient and reduces morbidity and pain. Three cases are reported with bladder complications arising from these recently advocated methods of management; two with external fixators and one with urethral catheter drainage. In one patient with an external fixator, stretching of the bladder over a bone fragment resulted in transient hematuria with activity. In a second patient, the protruding bladder wall was caught between opposing pubic rami. In an extraperitoneal bladder rupture with pubic rami fractures, urethral catheter drainage alone resulted in a pseudodiverticulum of the bladder with a bone fragment projecting through the hole in the bladder cavity. These cases illustrate some complications with these recently advocated methods of management of unstable pelvic fracture and ruptured bladder.

Adult↗
PubMed1983

Bending stiffness of unilateral and bilateral fixator frames.

The structural and geometric fixator properties that best neutralize the prevailing anteroposterior and transverse bending moments at a tibial fracture site were analyzed in anatomic specimens. Clinically and mechanically, anterior unilateral frames were most effective, particularly when applied with relatively stiff components with a maximal spread between the pins in each main bony fragment and with placement of the longitudinal rod close to the tibia.

Fracture Fixation↗
PubMed1983

Unilateral external fixation for severe open tibial fractures. Preliminary report of a prospective study.

In a prospective survey of severe open tibial fractures, the incidence of serious complications with relatively rigid one- or two-plane unilateral fixator frames was considerably lower than with internal fixation by plates and screws. Unilateral configurations that contain rigid components provide better wound access than bilateral frames and interfere less with knee and ankle motion; they allow unencumbered partial and even full weight-bearing. This increases comfort and mobility and may have a positive effect on fracture healing. No standard formula exists, however, for the application of an optimal unilateral frame. The clinical and mechanical demands of each patient and injury must be considered individually.

Adolescent↗
PubMed1981

Prototheca wickerhamii--an alga infecting the hand.

This report describes a hand infection caused by an alga. Prototheca wickerhamii. This rare organism presents most often as chronic dermatitis or bursitis of the upper extremity. Routine stains and cultures are easily confused with fungi. Only early, radical excision of the involved structures will effect a cure.

Adolescent↗
PubMed1981

Correlation of herpes simplex virus antibody titers and specific lymphocyte stimulation in adult blood donors.

Antibody titers to herpes simplex virus type 1 in sera from healthy adult donors were assayed by complement fixation, microneutralization, and an enzyme immunoassay (ELISA). This last test proved to be the most sensitive method for antibody detection. It was estimated that ELISA antibody titers were up to 40-fold higher than neutralizing antibody titers and up to 100-fold higher than complement fixation antibody titers. Due to the higher sensitivity of ELISA, only 3 of 36 blood donors tested in this assay were shown to be seronegative, whereas 6 additional persons of the same group were termed seronegative by the microneutralization assay. Furthermore, four of the latter also did not respond in the complement fixation test. In vitro stimulation of peripheral lymphocytes by using a partially purified herpes simplex virus type 1 particle antigen was achieved for all seropositive blood donors. Only those three donors who were ELISA negative reacted negatively in this stimulation assay. From these results it may be concluded that ELISA is an appropriate method not only for rapid and sensitive antibody determination but also for selecting herpes simplex virus-negative patients.

Adult↗
PubMed1980

The enzyme-linked immunosorbent assay (ELISA) for determination of IgG and IgM antibodies after infection with mumps virus.

Under routine laboratory conditions ELISA was tested for suitability for serological demonstration of specific antibodies of the immunoglobulin classes G and M against mumps virus. Sera from patients with known clinical and virological data were used. The results of ELISA were compared with those of CFT. 45 paired sera were tested in ELISA IgG, 87 first sera in ELISA IgM. Both tests were highly sensitive, antibodies were detected earlier and with higher titers than with the CFT. The ELISA IgM is particularly suitable for early diagnosis of mumps infection with the first serum. In addition 23 paired sera from patients with acute parainfluenza virus infection were examined for cross-reacting antibodies. Low anti-mumps IgG antibody titers were found in some sera. These findings reduced the mumps specificity of the IgG test. In five serum samples from one patient--obtained before, during, and after an infection with mumps--the course of IgG and IgM antibodies could be demonstrated. Advantages and limitations of ELISA IgG and IgM are summarized.

Antibody Formation↗