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Biomedical subjects

F Bessette

Publications and source records attributed to F Bessette.

10 recordsLinked to original sources

A method to express complex curves concisely and with high fidelity.

Piecewise spline interpolation between judiciously selected points on a curve reproduces it with great precision. A number of points much smaller than in current digitization techniques is needed and their positions fully characterize a curve. We present the rules to select the nodal points and we demonstrate that their positions are very sensitive to changes in wave form. They can therefore be used to identify a curve in parts or in its entirety, to provide its mathematical definition.

Animals↗

The liquid barrier filter: total protection against particulate contaminants.

The design, construction, and operation of a new type of filter that eliminates particulate contaminants from a current of gas is described. It has a yield higher than that of any conventional filter or filtration system. It is believed that a liquid barrier filter provides the best possible protection in all cases where not even a small number of toxic particulates can be tolerated in an atmosphere.

Air Pollution↗

The liquid barrier filter--a new concept to eliminate particulate contaminants from gases.

We have explored the possibility of using a continuous liquid phase of high gas permeability as a filter to remove particulate contaminants from a gas stream. The liquid, a non-toxic perfluorocarbon, severs upstream and downstream gas phases completely. It can dissolve great quantities of gases and pass them, by diffusion, along even a slight partial pressure gradient. The liquid phase remains intact in the process: there is no convective transfer of gas. Particulate contaminants will, on impact with the continuous liquid phase, lose their momentum and be stopped; our results promise near ideal efficacy of capture. We suggest that filters based on this principle be developed to protect against highly toxic particulate contaminants in an atmosphere.

Air Pollutants↗

[Phospholipids of pulmonary surfactants and lung elasticity].

We discuss the various preparations of substitute pulmonary surfactant that have been proposed for the treatment of Respiratory Distress Syndrome in premature infants. We than submit some experimental results demonstrating that a preparation of phospholipids in an organic solvent can simulate the behavior of the naturally occurring pulmonary surfactant as a monolayer at an air-water interface.

Humans↗

Reaction electrophoresis.

The differential mobilities of compounds in an electric field are important analytical criteria and we can use them to bring electrophoretically pure components of a mixture medium on which they are separated. To this end, the compound undergoing reaction are brought into positions on the carrier to assure optimal contact between selected fractions, within a predetermined domain of time and distance. The appearance of a product defines their reactivities, and the product's continued migration on the same carrier can provide the first key to its identity as is demonstrated and discussed. The method is called reaction electrophoresis and it will be of particular use in studies with labile components. It is illustrated here with the coupling reaction of the sodium salt of 1,4-naphthol sulfonic acid and tetrazotized o-dianisidine.

Azo Compounds↗

An endoscopic carrier with complete directional control: design principles.

We describe a carrier for instruments used in endoscopy. It consists of a train of articulated segments whose angular displacement is controlled by a series of magnetic clutches. The operator guides the leading segment under view from the carrier's proximal end, and the guide angle is repeated automatically at the articulations of all following segments. This mechanism is used to lead the entire length of the carrier around curves or flexures. A central channel accepts instruments for observation and manipulation. We believe that endoscopic examinations particularly of the upper and the lower digestive tracts will become much easier to perform with this new endoscopic sonde.

Biomedical Engineering↗

Automated electrocardiogram analysis: the state of the art.

The overwhelming number of electrocardiograms (ECGs) now recorded routinely has prompted the development of computer analysis which in turn has benefited electrocardiography with important technological advances. All automated ECG analysis systems adopt a similar approach: a measurement program and a program that interprets the clinical significance of these measurements along with a rhythm analysis algorithm. Measurement, selection and classification of parameters vary according to the program used. Data compression is applied to the signal to reduce processing time and allow long-term storage. Diagnostic accuracy, however, is not greatly improved over that of experienced cardiologists. Programs studied using a validated data bank provided by an international group of cardiologists show a variability not only in parameter measurement but also in diagnostic statement and in the way in which such statements are expressed. Recommendations for measurement standards have been made to fulfil the need for exchange of diagnostic criteria. No recommendations concerning the selection of parameters have been proposed, and so new parameters or combinations of parameters can be introduced with the ultimate aim of increased diagnostic performance.

Diagnosis, Computer-Assisted↗