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Biomedical subjects

F Bigar

Publications and source records attributed to F Bigar.

At least 37 records · Page 2Linked to original sources
PubMed1982

Corneal endothelial changes in primary acute angle-closure glaucoma.

In 20 patients, corneal endothelium was examined by specular microscopy after acute angle-closure glaucoma, and before any surgical treatment in order to assess possible damage during pressure induced abnormal hydration of the cornea. The mean intraocular pressure was elevated to 55 mm Hg and had lasted, on an average, 47 (5--192) hours. The mean endothelial cell density in the affected eye was 1534 and in the nonaffected fellow eye 2243 cells/mm2 (mean decrease 33%, P = 0.002). The amount of cell loss correlates with the duration of the intraocular pressure increase. Thirty-five percent of these patients presented a bilateral cornea guttata. This high incidence of endothelial dystrophy was confirmed in a retrospective specular microscopic study in 20 patients with a history of unilateral acute angle-closure glaucoma. The decreased number of endothelial cells after acute angle-closure glaucoma frequently combined with bilateral cornea guttata, accounts for the corneal degeneration in these patients following a later cataract extraction.

Aged↗
PubMed1982

[Corneal Endothelial changes after insertion of iridocapsular (Two-loop) lenses (author's transl)].

The corneal endothelial damage in extracapsular extraction and insertion of a two-loop lens (Binkhorst) using the deep chamber technique was investigated by specular microscopy. The endothelial cell loss in 25 patients was 15%. During a mean postoperative period of 15 months a further endothelial cell loss of 5% occurred. The effect of a direct contact between an intraocular lens and the corneal endothelium is demonstrated by a case of luxation of a two-loop lens into the anterior chamber.

Adult↗
PubMed1981

[Primary wound closure after eye injuries. An analysis of 100 cases (author's transl)].

Penetrating eye injuries occur frequently during children's games or in the household, are caused by road accidents or at work. Of a series of 100 consecutive primary wound repairs 89% were perforation and 11% ruptures of the globe. In 53% of the analyzed injuries the wound was limited to the cornea, in 29% to the sclera and in 18% there was a combined corneoscleral wound. The lens and the vitreous were injured in one-third of the cases. The aim of the primary repair in penetrating injuries of the anterior segment is a watertight wound closure and the reconstitution of the anterior chamber. Intraocular foreign bodies are extracted in an atraumatic manner after exact localization. In extensive injuries of the posterior segment an adequate retinal detachment prophylaxis is part of the primary wound repair. The final result after rupture of the globe is rather unsatisfactory. The result in penetrating injuries is better and depends on the extent of the changes of the bulbar wall and the involvement of the intraocular structures. In the treatment of eyes with penetrating injuries the functional results are good in about 30%.

Adolescent↗
PubMed1980

[Cornea guttata in specular microscopy (author's transl)].

The specular photomicrographic appearance of cornea guttata is described in both donor material and in patients. Furthermore, an analysis of endothelial cell density in patients with cornea guttata is presented and compared with cell density in the normal population in the same age group. The mean endothelial cell size in 16 eyes with cornea guttata was significantly larger than in 20 normal eyes of persons between 70 and 79 years of age.

Aged↗
PubMed1979

[Combined use of computerized tomography and echography in ophthalmology (author's transl)].

Computerized tomography does not give as fine an information as echography in the presence of intraocular changes, such as retinal detachments, organized vitreous hemorrhages or the differentiation of a choroidal prominence. Complementary computerized tomography, however, can be helpful in the presence of unclear echographic results in opaque media. Furthermore, an analysis of the value of computerized tomography and echography for the evaluation of orbital lesions is presented based mainly on the results of the preoperative tissue diagnosis in 31 histological proven lesions. The results show that a complementary CT-scan is not necessary in orbital lesions of the anterior third when a clear echographic tissue diagnosis exists. In lesions of the middle third of the orbit, echography and CT complement each other. For lesions situated within the orbital apex or for those which are in connection with adjacent structures, such as the intracranial space or the periorbital region, computerized tomography is superior and of a greater help than standardized A-scan echography aided by contact B-scan.

Eye Diseases↗
PubMed1978

Cornea guttata in donor material.

Specular microscopy made it possible to detect cornea guttata changes within the regular reflection off the posterior surface of the cornea in donor matrial. Small, roundish lesions were present in mild forms within an otherwise intact endothelium, and in advanced cases, large warts were seen free of endothelial cell coverage.

Aged↗
PubMed1978

[Acute iridocyclitis, ankylosing spondylitis (Bechterew) and congenital tissue antigens (author's transl)].

The tiysue antigen HLA-B27 was present in 92.6% of 95 Swiss patients with classical ankylosing spondylitis. This tissue antigen is present in only 7.7% of healthy Swiss blood donors. 36% of all patients had one or several acute attacks of anterior uveitis. This usually follows the onset of joint symptoms. In 4% of the 95 patients the iritis was the first symptom. The combination of acute uveitis and ankylosing spondylitis with the tissue antigen HLA-B27 indicates that not only the spondylitis, but also the uveitis is in many cases genetically determined.

Acute Disease↗
PubMed1978

[Specular microscopy of the corneal endothelium (author's transl)].

Specular microscopy enables the examination of the endothelium of the isolated and perfused cornea. It is of great help in evaluating donor material in an Eye Bank. The in vivo observation and microphotography of the corneal endothelium makes it possible to detect early degenerative, traumatic surgical and other pathological changes of the monolayer.

Adult↗
PubMed1977

[Combined A- and B-scan echography of the eye (author's transl)].

The combined use of A- and B-scan echography gives far better diagnostic results than either one used alone. Both methods have their advantages and disadvantages and each complements the other. A-scan echography provides more information about the structure of a lesion. B-scan is better in demonstrating the topography of a lesion. For A-scan echography the standardized unit 7200 MA Kretz-Technik is used; for B-scan the practical Bronson-Turner contact B-scan be used. Opaque media are the main indications for echography of the globe. However, echography is also indicated in the presence of clear media for the differential diagnosis of solid lesions.

Eye Diseases↗
PubMed1977

Combined A- and B-scan echography. Preoperative evaluation of vitrectomy patients.

The preoperative ultrasound evaluation of vitrectomy patients is of great value. The combined use of an optimized and standardized A-scan and B-contact scan echography gives good results. While the A-scan echography gives information about the quantitative and kinetic characteristics of the examined structures, B-scan echography demonstrates, in addition, the shape and topographic relationship of the investigated structures. The combination of A-scan and B-scan echography is not time-consuming and does not inconvenience the patient as does the use of an immersion water bath. The results of 105 echographically evaluated vitrectomy patients are presented.

Eye Diseases↗
PubMed1976

Routine evaluation of endothelium in human donor corneas.

Specular microscopy allows a direct evaluation of the corneal endothelium in intact donor eyes. It is therefore superior to previous methods for assessing donor material for penetrating keratoplasties. In a study of 278 eyes (139 donors) 226 could be examined by specular microscopy without any preparatory major manipulations. Twenty-four pairs and 12 single eyes (27%) of the 226 corneas were considered not suitable for grafts according to their morphologic endothelial changes. The discarded eyes were found all normal at conventional slit-lamp examination. Specular microscopy of the endothelium was not possible in 52 eyes as the corneal swelling was already too advanced.

Adolescent↗