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F Blanchon

Publications and source records attributed to F Blanchon.

47 records · Page 3Linked to original sources

[Etiology of hemoptyses].

From hemoptyses as main symptom for the admission of patients during 1975 and 1976 in the pulmonary disease department of a parisian hospital, a retrospective study of the causes of hemoptyses is made by the authors. In 18% of the cases, hemoptysis was the unique revealing symptom of the disease. Tuberculosis and cancer are the main causes, but, now, their rate is inverted : 30% for cancer, 21% for tuberculosis, but in addition there are 9% in relation with sequelae of tuberculosis. Among the other causes, bronchiectases keep an important place, just as cardiovasculary diseases. But there is a portion of patients for whom the cause of the hemoptysis cannot be found. As bronchologic and vasculary explorations are developed, this portion of patients will diminish but will not disappear, because mechanisms of hemoptysis will be better explained but not the real cause.

Bronchiectasis↗

[Destroyed lung (author's transl)].

The expression of "destroyed lung" is, now, accepted to designate the large destructions of the lung, secondary to pulmonary and essentially infectious diseases, the cure of which is obtained but with important sequelae. The main cause remains tuberculosis, cured by chemotherapy. Some large pulmonary suppurations, treated by antibiotics, can lead to the same sequelae. These "destroyed lungs" can keep an asymptomatic form. But often, about ten years after the initial disease, they cause several troubles such as progressive dyspnea leading to irreversible respiratory insufficiency, repeated pulmonary infectious episodes and hemoptysis, the risk of which is increased by aspergillosis. The radiological aspect of these "destroyed lungs" is made of opacities with multiple cavities or with one unique large cavity. The mechanism of hemoptysis has been understood recently: all destructive lesion of the pulmonary tissue produces as a consequence a development of the systemic blood circulation, bronchial or parietal, with reverse blood circulation from systemo-pulmonary anastomoses-which can produce capillary dilatations-into the pulmonary artery. All these complications can lead to a surgical treatment. Embolization of bronchial arteries is a less aggressive method when hemoptysis is the main symptom. These acquires "destroyed lungs" can be compared to those caused by extensive pseudokystic bronchiectases. For both cases clinical aspects and therapeutic methods are similar, though the lesions are fixed and likely congenital in the last form.

Adult↗

[Clinical aspect and actual frequency of bilateral squamous cell bronchial carcinoma with simultaneous revelation (author's transl)].

Clinical and physiopathological data about 10 cases of bilateral squamous cell bronchial carcinoma with simultaneous revelation, are reviewed. This clinical form is not rare, usually found by a systematic bilateral endoscopy. In these 10 cases, the clinical and radiological data did not allow to predict the diagnosis before the endoscopy. Physio-pathological mechanisms are not well established. Various hypotheses are propounded : air-way, blood or lymphatic metastases, simultaneous tumoral blossoming, superficial propagation, genetic factors intervention. For these 10 cases, the authors develop arguments for one or another of these mechanisms.

Aged↗

[Carcinoid tumor of the thymus: report of a case (author's transl)].

Carcinoid tumor primarily developing in the thymus gland is very rare. A new case is reported to add to the 35 previously reported. In most cases, patients have no endocrinological syndrome; the tumor is rarely associated with a multiple endocrine adenomatosis. This neoplasm probably derived from Kultschizky cells which are present in the normal thymus gland. Histologically they are very similar to the carcinoid tumor of other organs. Complete surgical excision is the best treatment when possible.

Apudoma↗

[Clinical and evolutive characteristics of bronchial cancers discovered by systematic X-ray examinations (author's transl)].

The characteristics of broncho-pulmonary cancers discovered during systematic X-ray were studied over an 11 year period by comparison with cancers discovered through their symptoms. The operability of first group patients was definitely superior (62.5% against 36.7%y and so was the 5 year survival (18.7 against 5.5%). These differences are statistically significant and should be remembered, before the results of extensive anglo-saxon surveys be known, about the value of X-ray detection of bronchial cancer--at least in high risk patients.

Adenocarcinoma↗

[Bi-apical pulmonary fibrosis during ankilosing spondylitis: A report on 5 cases (author's transl)].

The authors describe 5 cases of bi-apical pulmonary fibrosis occurring during the course of ankylosing spondylitis. In 4 patients the lesions were advanced and detected during pneumological investigations. In the 5th patient, the lesions were at an early stage and were discovered during a retrospective study of 100 case-reports of patients with ankylosing spondylitis. Radiological signs were morphologically similar: localized pulmonary lesions of the two apices, of the retractile type and with a fibrous hilar framework, bullous images that were more or less extensive, raising of the two hili with compensatory distention at both bases, and pleural lesions consisting of thickening of both pleurae at the apices. The mean age of the patients at the time these lesions appear is 60 years, and they occur about 20 years after the onset of the articular disorder. These fibro-bullous lesions can be complicated by aspergillosis (20%) of pneumothorax (8%). The principal differential diagnosis is advanced tuberculous disease in the lung apices, and this explains why these patients have often been prescribed antituberculosis therapy.

Adult↗