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Biomedical subjects

F Blank

Publications and source records attributed to F Blank.

At least 19 recordsLinked to original sources
PubMed1977

Enigmatic relationship of two Microsporum species.

Unusual cultures of a Microsporum species were isolated from eleven patients who had either tinea capitis or tinea corporis or both. Although the macroconidia produced in the primary cultures resembled those of M. canis, hyphal morphology and colony characteristics were different from any of the more commonly occurring Microsporum species. Careful examination of subcultures showed that the isolates were composed of two species; M. canis and M. distortum, whose relationship remains enigmatic.

Adult↗
PubMed1976

Peptido polysaccharide antigens from Trichophyton mentagrophytes var. granulosum.

Two highly purified peptido polysaccharide antigens have been isolated from surface-grown cultures of Trichophyton mentagrophytes var. granulosum. Trichloroacetic acid extraction and ethanol precipitation yielded a mixture containing high-molecular-weight components which were first separated on Sephadex G-200. Subsequent fractionation by ion-exchange chromatography on DE-52-cellulose (borate form) yielded the two peptido polysaccharides. Both of the peptido polysaccharides reacted with rabbit antiserum to T. mentagrophytes var. granulosum. The two peptido polysaccharides contain 73.2% hexoses (mannose-galactose-glucose, 7.5:0.7:1), 8.6% amino acids and 1.8% amino sugars and 77.4% hexoses (mannose-galactose-glucose, 9:0.3:1), 6.2% amino acids, and 0.4% amino sugars, respectively. Each contains 16 different amino acids, threonine, proline, and serine predominating.

Antigens, Fungal↗
PubMed1976

Caffeic acid-containing medium for identification of Cryptococcus neoformans.

A new growth medium containing caffeic acid and ferric citrate is described. The pigment produced on this medium is specific for the identification of Cryptococcus neoformans and differentiates it from other cryptococci. The medium is more easily compounded and requires less time for pigment formation than the conventional Guizotia extract media. The medium is stable in the dry form as well as in the prepared form.

Caffeic Acids↗
PubMed1975

Trichophyton rubrum infections according to age, anatomical distribution and sex.

Trichophyton rubrum caused 72.9% of the cases of dermatophytosis observed in a sample of caucasoids from Philadelphia. Tinea pedis was found in 84% of the female and male patients with dermatophytosis. Tinea manuum occurred with equal frequency in both sexes whereas tinea unguium was more prevalent in females. Tinea cruris occurred almost exclusively in males. Infections of two or more anatomical sites were observed more frequently in males. The data are compared with those reported by Rosman (1966) from a similar study done in Copenhagen.

Adolescent↗
PubMed1975

Systemic amyloidosis in mice inoculated with lyophilized Candida cells.

Injection of lyophilized Candida albicans or C. parapsilosis cells induced amyloidosis in outbred CFW mice. The disease process was irreversible, and a significant number of animals died of systemic amyloidosis within 400 days after the last treatment. The techniques described may represent a model system for the study of systemic amyloidosis.

Amyloid↗
PubMed1975

Antibodies with affinity for epithelial tissue in chronic dermatophytosis.

Antibodies to dermatophytes which also had affinity for intercellular material of epithelial tissue, were detected in sera from 80% of patients with chronic dermatophytosis using an indirect fluorescent antibody test. The class of immunoglobulins reactive with both the dermatophyte and the epithelial tissue was identified as IgM. IgM antibodies with affinity for arthrospores of Trichophyton mentagrophytes and intercellular substance of epithelial tissue could be removed from sera with mycelium of Trichophyton rubrum.

Adult↗