Biomedical subjects
Publications and source records attributed to F Bouabdallah.
The plasmid profile of 28 multiresistant Salmonella serovar Wien strains isolated between 1985 and 1990 is described. Four types of plasmids were individualised. Among these plasmids, two were responsable for beta-lactam resistance, type I plasmid of 110 kb and type II of 30 kb.
Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen in hospitals. Between 1985 to 1988, there has been an increase in the number of MRSA (92 %) caused by an epidemic emergency in medical care unit of our hospital. Infections control measures allowed to stop these outbreaks (20 % MRSA in 1990). But incidence of MRSA persist to decrease without supplement control measures and in 1994, only 7 % of Staphylococcus aureus strains are MRSA.
A serious epidemic of Acinetobacter baumannii resistant to imipenem occurred in the surgical intensive care unit of the hospital Charles-Nicolle in Tunis during February 1994, causing two deaths among three patients. The Acinetobacter strains were isolated from various samples of the intensive care unit. The techniques used for typing were biotyping, antibiogram, plasmid profiles and chromosomal DNA by random amplified polymorphic DNA (RAPD). The A baumannii strains isolated from patients exhibited an identical pattern with all the epidemiological markers utilized; the strains from the surrounding areas showed four and six different patterns respectively for phenotypic and genotypic characters. The strain isolated from a care table had the same phenotypic and genotypic pattern as that of the patients' strains.
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