PubMed Health⌕ Search

Biomedical subjects

F Bouissou

Publications and source records attributed to F Bouissou.

49 records · Page 3Linked to original sources
PubMed1980

[Pediatric renal transplantation in Toulouse (author's transl)].

The regional group of renal transplantation in Toulouse includes a medico-surgical team which participates to all the activities of this group. Dialysis and transplantation are covered in a center organized for the care of children. This branch is part of the Regional Hospital. From 15 years old on patients are moved from the pediatric branch to the medico-surgical center taking care of adults. Both teams within the regional hospital share the responsability of taking off kidneys from cadaveric donors and collaborate to France-Transplant and Euro-Transplant. Since the pediatric center in charge of renal failure has opened, 32 children underwent chronic hemodialysis. Some of these patients are presently treated in the center for adults. Fourteen children were grafted and seven are at this moment waiting to receive transplantation. The average number of transplantations per year is from 1 to 4. These fourteen children underwent renal transplantation with kidneys from cadaveric donors. Only one has been provided by Toulouse. Diuresis resumed immediately in 8 cases, later in 5. An extremely acute reject was observed in one case and transplantectomy had to be performed 10 days after transplantation. Eight children presented acute reversible reject which, for 4 of them, evoluated towards chronicle reject. Eight children presented a chronicle reject: 4 of them are again in dialysis. Altogether 8 kidneys are functioning (seven years in the longest case). Five children resumed chronic dialysis. One patient died of acute pancreatitis. He underwent a portocaval shunt for type I glycogenosis which ended in a hyperuricemic nephropathy evoluating towards renal failure forcing a transplantation. The rehabilitation of transplanted children was always satisfactory.

Adolescent↗
PubMed1980

Severe idiopathic nephrotic syndrome with tubular dysfunction (report of nine pediatric cases).

The association of idopathic nephrotic syndrome (INS) with tubular dysfunction is uncommon. The authors report on 9 pediatric cases (6 girls and 3 boys). All the patients (age 12 to 48 months) presented initially with a pure INS. The syndrome was clinically severe and either initially or secondarily resistant to steroid and immunosuppressive therapy. In 6 cases initial renal biopsies showed minimal glomerular lesions and in one case, segmental and focal hyalinization was observed. Symptoms of tubular insufficiency appeared progressively and included: proximal and distal hyperchloremic acidosis (9/9 cases), renal glycosuria (9/9 cases), hypokalemia with hyperkaluria (7/9 cases), hypohposphatemia (4/9 cases), global hyperaminoaciduria (4/9 cases), tubular proteinura (2/9 cases). Control of water and electrolyte balance was difficult. The urinary concentration of fibrinogen breakdown products was very high throughout the course of the disease. In all cases, anemia preceded the inevitable alteration of glomerular filtration which resulted in four cases of terminal renal failure after an average evolution of 2 to 3 years. Renal biopsies during the later stages of evolution demonstrated five cases of glomerular hyalinization with interstitial fibrosis associated in 3 cases with histiocytic infiltration. Immunologic studies were negative. The authors discuss the physiopathologic aspects of the disease including the possibility of thrombosis of intrarenal veins and compare their observations with those of Royer et al. [1963].

Acute Disease↗
PubMed1980

[Urinary excretion of fibrin degradation products in children with nephrotic syndrome (author's transl)].

In glomerular disease the urinary excretion of fibrin degradation products (FDP) has prognostic value. In a prospective longitudinal study of 120 cases of idiopathic nephrotic syndrome the urinary FDPs have been measured. The results have been correlated to the proteinuria, plasma FDPs, the renal biopsy appearance, the response to steroid therapy and the outcome. During relapse in steroid sensitive or dependent nephrotic syndrome the urinary excretion of FDPs is low. In steroid resistant nephrotic syndrome with a poor prognosis there was a prolonged and raised excretion of FDPs (> 3 micrograms/ml) that preceeded the phase of progressive renal failure and corresponded to glomerular segmental hyalinisation. The significance of this finding is not clear. Fibrinogen is probably filtered in the glomerulus with subsequent fibrinolysis in the urine. This mechanism is proposed because of the inverse correlation between urine FDPs and the selectivity of the proteinuria, variable plasma FDP levels and only occasional deposition of fibrin in the glomerulus.

Adolescent↗
PubMed1979

[Distal renal tubular acidosis: report of 3 cases].

Three observations of R.T.A. with nerve deafness are reported. Case 1 and 2 concern consanguinous brothers whose parents are not affected, which confirm the syndrom as an autosomal recessive entity. The third, sporadic, case relates to a 13-year-old non consanguinous girl. Metabolic abnormalities and renal evolution with nephrocalcinosis was such as in Albright disease. However a progressive nerve deafness makes distinction. The authors underline the importance of this sometimes difficult distinction for genetic counseling.

Acidosis, Renal Tubular↗