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Biomedical subjects

F C Kuipers

Publications and source records attributed to F C Kuipers.

18 recordsLinked to original sources

Multifocal recurrent periostitis responsive to colchicine.

A brother and sister with multifocal recurrent periostitis are presented. Their disease started at an early age and manifested itself as an episodic migrating arthropathy. At roentgenography, reversible solid periosteal reactions were visible along large tubular bones. Scintigraphic and histological investigations revealed a sterile osteitis and thickened periosteum, but there was no indication of a viral infection. The girl experienced spontaneous amelioration after puberty; the boy improved markedly on colchicine.

Adrenal Cortex Hormones

Are rheumatoid nodules caused by vasculitis? A study of 13 early cases.

Rheumatoid nodules are especially found in patients with seropositive rheumatoid arthritis (RA). It is often suggested that the genesis of these lesions is due to a vasculitis in smaller capillary vessels or venules. To test this hypothesis we studied fresh nodules in 13 patients, all with classical or definite RA. In 7 cases a total of 8 nodules were removed within 10 days of origin and in 6 other cases between 2 and 8 weeks. In the former group immunofluorescence was found in 5 out of 8 cases, and in the latter group 3 out of 6 were positive. Immunoglobulin deposition together with complement was found only in cases of 10 days' duration or less. No correlation was found with the patient's age or disease duration, ESR, ANA positivity, Rose titre, haemoglobulin, or use of prednisolone. In 3 out of 7 nodules younger than 7 days no palisade layer was found, whereas in older nodules this layer was always present. Vasculitis was not more frequently present in the cases with younger nodules. Our study does not support the hypothesis that vasculitis is the primary cause of nodules.

Aged

Case report: false aneurysm due to synovial sarcoma.

On the basis of a false aneurysm of the radial artery caused by a synovial sarcoma, the behavior and histology of this fairly rare tumor are discussed. There are no reports in the literature which record such a rapidly developing synovial sarcoma as that observed in the patient described here.

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