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Biomedical subjects

F C Powell

Publications and source records attributed to F C Powell.

At least 19 recordsLinked to original sources
PubMed1992

Schirmer testing for dry eyes in patients with rosacea.

BACKGROUND: Dry eyes have been reported in a significantly greater number of patients with ocular rosacea than in control subjects. OBJECTIVE: Our purpose was to assess the incidence of dry eyes in patients with cutaneous rosacea and to compare this with a control population. METHODS: With the use of the Schirmer test without anesthesia, the amount of aqueous tear secretion of 32 consecutive patients (16 women, 16 men) with rosacea was compared with that of 32 psoriasis patients (16 women, 16 men) without rosacea who served as age- and sex-matched controls. Two criteria, 5 mm and 8 mm of strip wetting, were used to indicate the lower limit of normal aqueous tear secretion. RESULTS: Of rosacea patients, 56.3% had less than 8 mm of strip wetting compared with 25% of control patients (p less than 0.02). Of rosacea patients, 40.6% had less than 5 mm of strip wetting compared with 18.75% of controls (p less than 0.10). CONCLUSION: The results of this study suggest that dry eyes occur frequently in rosacea. It is important that dermatologists and ophthalmologists be aware of the frequency of dry eyes in rosacea, so that patients are investigated and appropriate therapy can be provided.

Adult↗
PubMed1992

Pyoderma gangrenosum, polycythemia rubra vera, and the development of leukemia.

A patient with long-standing, well-controlled polycythemia rubra vera developed recurrent episodes of bullous pyoderma gangrenosum followed by the transformation of his hematologic disease into a rapidly progressive acute myeloid leukemia. This case, together with previously described patients, indicates that the appearance of bullous pyoderma gangrenosum in a patient with polycythemia rubra vera is often of ominous prognostic significance.

Humans↗
PubMed1992

Rural and urban elderly construe health differently.

Samples of people aged 65 or older (N = 396) living in the metropolitan Omaha area and in the rural Sandhills counties of central and western Nebraska completed an instrument to assess health satisfaction, health behaviors, and attitudes toward health care. Few intergroup differences were found that could be attributed to the area of residence. However, factor analysis and item analysis of the attitudes toward health items indicated that older respondents in rural areas may have very different perceptions of health in general and of health care services in particular than those of elderly urban residents.

Aged↗
PubMed1992

Generalized elastosis perforans serpiginosa in Down's syndrome.

Elastosis perforans serpiginosa is a rare disorder of epidermal perforation characterized by the extrusion of dermal elastic tissue through the epidermis. Its aetiology is unknown, but there is histological and biochemical evidence of an abnormality of elastic tissue. Three forms of elastosis perforans serpiginosa exist. It may be either idiopathic, iatrogenic, or, in approximately one quarter of cases, associated with certain genetically determined disorders of connective tissue. Cutaneous lesions appear between the ages of 6 and 20 years, and persist for 6 months to 5 years. They may be confined to one anatomic area, or less frequently are disseminated. We review the case of a 28-year-old woman with recent onset of unusually extensive elastosis perforans serpiginosa with co-existing Down's syndrome and (secondary) sclerosing cholangitis.

Adult↗
PubMed1992

Familial non-diabetic necrobiosis lipoidica.

Necrobiosis lipoidica (NL) is a cutaneous disorder with distinctive clinical and morphologic characteristics. It is associated with diabetes mellitus in two thirds of cases. The aetiology and pathogenesis of NL are unknown but familial cases of NL seem to be extremely rare. We report the occurrence of NL in two sisters with normal glucose tolerance.

Biopsy↗
PubMed1991

Polymorphic light eruption with contact and photocontact allergy.

We report a patient with long-standing polymorphic light eruption (PLE) who developed a photocontact allergy to mexenone and several contact allergies. The occurrence of multiple contact and photocontact allergies in PLE and the possible relationship of such allergies to the pathogenesis of PLE are discussed.

Aged↗
PubMed1991

Necrobiosis lipoidica and sarcoidosis.

We report the case of a female patient with necrobiosis lipoidica of the lower legs and coexistent systemic and cutaneous sarcoidosis. We review the six previously reported patients with coexisting necrobiosis lipoidica and sarcoidosis. The associations between the granulomatous disorders of the skin, especially necrobiosis lipoidica, sarcoidosis and granuloma annulare, are discussed. The common pathogenetic features of these disorders are reviewed.

Female↗
PubMed1991

Medical students' attitudes towards ageing and death: a cross-sequential study.

This study presents an analysis of possible changes in attitudes towards older persons and in attitudes towards personal death anxiety that might occur over the course of undergraduate medical education. Three entering classes of medical students at a university in the Mid-western United States completed an attitudes towards old people scale, a death anxiety scale, and a standard personality inventory. As graduating seniors, they again completed the attitudes towards old people scale and the death anxiety scale. Significant changes did not occur. In comparison with baseline data from a group of 212 university graduate students in the USA, these 234 medical undergraduates had significantly more positive attitudes towards the aged; in another comparison, their death anxiety was significantly lower than a group of 599 from the general population. Implications are discussed.

Adult↗
PubMed1991

Epidermolysis bullosa and aplasia cutis.

Recessive dystrophic epidermolysis bullosa with aplasia cutis occurring in a male infant is described. The association of these two rare conditions is reviewed. Reports of the concurrence of large areas of congenital absence of skin, particularly on the lower limbs, in patients with several different types of epidermolysis bullosa suggest that areas of congenital absence of skin in these patients are an initial manifestation of the bullous disease rather than a distinctive entity.

Epidermolysis Bullosa Dystrophica↗
PubMed1991

Extramammary Paget's disease and prostatic carcinoma.

A patient with perianal extramammary Paget's disease (EMPD) occurring simultaneously with prostatic adenocarcinoma is presented. Four previously reported cases of genital EMPD associated with prostatic carcinoma are reviewed. The use of immunohistologic techniques to help establish the diagnosis in some cases, and the relationship of EMPD to underlying adenocarcinoma of sweat glands and of the lower urinary and gastrointestinal tracts is discussed. The importance of a directed search for internal malignancy in the individual patient with EMPD is emphasised.

Adenocarcinoma↗
PubMed1991

Age differences in health attitudes and beliefs.

In a telephone interview, samples of 196 older and 280 younger adults completed a series of 24 items designed to assess health beliefs. Differences may have implications for health care expenditures now and in the future.

Aged↗