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Biomedical subjects

F Cacciapuoti

Publications and source records attributed to F Cacciapuoti.

52 records · Page 3Linked to original sources
PubMedDate not supplied

Hemodynamic effects of somatostatin in insulin-dependent diabetic subjects.

The aim of the present study was to evaluate possible hemodynamic effects of somatostatin in insulin-dependent diabetic subjects. For this purpose, 7 insulin-requiring juvenile-onset diabetics were submitted to a short-term infusion of cyclic somatostatin (250 micrograms/h, over 2 h) or saline in randomized order. Somatostatin infusion resulted in a progressive and significant decrease in heart rate, stroke volume, cardiac index and velocity circumferential fiber; on the other hand, left ventricular ejection time was augmented by somatostatin. None of these effects was seen in the saline control study. We conclude that somatostatin exerts a negative inotropic effect in insulin-dependent diabetes.

Adult↗
PubMedDate not supplied

[Surgical treatment and interventional therapy in cerebral ischemia].

The aim of this review was to evaluate the possibility of correcting cerebral ischemia (including both extracranial varieties) using elective as well as emergency surgery in order to avoid the onset of acute cerebral ischemia. The study included patients suffering from cerebral ischemia with a thromboembolic etiology. The author describe the emergency surgical procedures currently used in embolic forms affecting the extracranial vessels and percutaneous transluminal angioplasty (PTA) which is confined solely to extracranial vessels at present. In the authors' opinion, this method (with or without the application of one or more stents) will soon represent the routine method of cerebral revascularisation in the near future. The authors review the results currently obtained using extracranial PTA in the main brain surgery centres worldwide, the most frequent complications and the problems still to be resolved. In conclusion, it is useful to use interventional procedures to treat both extracranial and intracranial lesions in order to significantly reduce mortality from acute cerebral ischemia and its functional sequelae.

Brain Ischemia↗
PubMedDate not supplied

[Behavior of hemodynamic and blood-gas parameters after intravenous salbutamol].

The haemodynamic effects of salbutamol were studied in 14 patients with chronic obstructive lung disease with a single dose of 100 and 200 gamma, administered by i.v. injection. The results of study revealed salbutamol intravenous injection significantly increases heart rate, cardiac index and decreases vascular systemic resistance. There was no significant change in blood gas tensions. This study indicates that salbutamol produces variation in preload and afterload by a direct action on vascular smooth muscle.

Albuterol↗
PubMedDate not supplied

[Polygraphic study of systolic rates after intravenous administration of salbutamol].

The effects of salbutamol on the polygraphic pattern were studied in 10 patients with chronic obstructive lung disease. Salbutamol, administered by i.v. injection in a single dose of 100 gamma, caused an increase of heart rate, a decrease of PEP (by decrease in the TCI), a decrease of the Wessler's index and an increase of ejection fraction. These results suggest that salbutamol produces an improvement in cardiac function either by a direct inotropic action or by an afterload decrease.

Adult↗
PubMedDate not supplied

[Echocardiographic assessment of left ventricular function after intravenous administration of salbutamol].

Changes in the main parameters of left ventricular function by comparison with the baselines were examined echocardiography in 11 patients after a single i.v. dose of salbutamol. The results suggest that salbutamol certainly has peripheral vascular effects leading to changes in ventricular volumes. The drug also appears to exert a positive intropic action, as shown by the changes it induced in EF and, more particularly VCF values.

Adult↗