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F Calero

Publications and source records attributed to F Calero.

At least 37 records · Page 2Linked to original sources
PubMed1990

Hematologic data in 825 cases of beta-thalassemia trait in Spain.

We present the hematologic data of 825 cases of beta-thalassemia trait (687 cases of beta-thalassemia trait and 138 cases of delta beta-thalassemia trait). There were no significant differences between the red cell indices of the patients with beta and delta beta-thalassemia trait. In patients with beta-thalassemia trait, MCV was significantly reduced in 97% of the males and 99% of the females. All the patients with delta beta-thalassemia trait showed low MCV values. Red cell morphology was altered in the vast majority of cases, with basophilic stippling in 96% of the patients. Most patients came from provinces with the highest incidence of malaria in the past.

Adolescent↗
PubMed1990

Alpha thalassaemia in two Spanish families.

Two Spanish families with alpha thalassaemia, including 4 individuals with Hb H disease, are described. DNA mapping shows that, in addition to the common alpha thalassaemia determinant (-alpha 3.7), a different and previously unreported allele is present in each family. In one, there is a deletion of 10.5-12 kb of DNA including both alpha genes (--SPAN). In the other, a deletion of more than 100 kb has removed the entire alpha globin gene complex (--BR).

Alleles↗
PubMed1989

A new Spanish family with Hb Louisville.

The clinical, hematological, and biochemical characteristics of a new family with heterozygous hemoglobin (Hb) Louisville are described. The family showed a decrease in both oxygen affinity and cooperativity with the normal Bohr effect. This family has the greatest number of affected members reported to date. Among the descendants, two first cousins (III-10 and III-11), both of whom are affected by the heterozygous trait of Hb Louisville, had had three abortions of undetermined causes.

Adult↗
PubMed1987

A new family with hereditary choreo-acanthocytosis.

We describe a new family with hereditary choreo-acanthocytosis. Two members of this family were affected; neither of them suffered from anaemia or signs of haemolysis. The acanthocytes showed an impaired deformability with an increase in whole blood viscosity. The composition of the plasma and erythrocyte membrane lipids was normal, as was the fatty acid composition of the erythrocyte ghost membranes. The only alteration found was a decrease in the fluidity of the erythrocytic membrane.

Acanthocytes↗
PubMed1986

Haemoglobin Presbyterian [beta 108 (G 10) Asn----Lys] in a Spanish family.

Clinical, haematological and biochemical aspects of a new family with heterozygous haemoglobin Presbyterian [beta 108 (G 10) Asn----Lys] are described. It could be readily separated by isoelectric focusing, DEAE-cellulose chromatography and by cation exchange high-performance liquid chromatography (HPLC). The characterization of this mildly unstable haemoglobin was made by reverse-phase HPLC. This is the fourth family with Hb Presbyterian so far described.

Adult↗
PubMed1984

[Definition of intrauterine growth retardation].

In order to answer the question as to the limit of intrauterine foetal growth retardation, we compared three weight values at birth: two standard deviations below the mean, namely the fifth and tenth percentiles. The comparisons were made on the intrapartum and early neonatal mortality rates of 19,256 infants born during 1980 in "La Paz" Maternity Hospital of Madrid. Our results show that we have to consider as newborn with a growth retardation those infants whose weight at birth is lower than the fifth percentile for their gestational age and sex. In this group of infants, the intrapartum and early neonatal mortality rates are significantly higher than among newborn with a superior weight. At the same time, we found that the mortality among newborn with a weight between the fifth and tenth percentile was not significantly higher than that observed among infants with a weight at birth greater than the tenth percentile.

Birth Weight↗
PubMed1983

Haemoglobin LeporeBaltimore in a Spanish family.

Description of the clinical, haematological and biochemical aspects of a new family with heterozygous haemoglobin LeporeBaltimore. Of the 6 members affected. 4 were totally asymptomatic. All of them showed morphologic features of heterozygous beta-thalassaemia. The levels of haemoglobin Lepore ranged from 12.2 to 15% (mean value: 13.7 +/- 1.1%). The analysis of the primary structure of the haemoglobin shows that crossing over takes place between amino acid 50 of the delta-chain and amino acid 86 of the beta-chain. This is the third family, to our knowledge, with haemoglobin LeporeBaltimore so far described.

Adolescent↗