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Biomedical subjects

F Carnot

Publications and source records attributed to F Carnot.

At least 127 records · Page 7Linked to original sources
PubMed1982

[Pneumoblastoma. Review of the literature apropos of a case].

Pneumoblastoma is a rare pulmonary malignant tumor, demonstrating atypical histological features analogous with the epithelial and mesenchymatous formations associated in the embryonic lung. Their dysembryoplastic origin, suggested initially because of these appearances, is currently contested in favor of a neoplastic origin. They are rare tumors, but they still stimulate interest because of certain particular features related to their course, and because of the problem of their histogenesis.

Diagnosis, Differential↗
PubMed1980

[Sarcoidosis and portal and pulmonary arterial hypertension: a case report (author's transl)].

A 27-year-old patient, originally from Martinique, presented with a progressive hepatic granulomatosis with hepatomegaly, splenomegaly, and non-icteric cholestasis, associated with bronchial granulomatosis lesions. The sarcoidosis regressed rapidly after high doses (60 mg/day) of prednisone. Portal hypertension developed later and provoked a severe hematemesis from rupture of esophageal varices. Signs of pulmonary arterial hypertension were then observed, and the diagnosis confirmed by pressure tests after catheterization, and angiography. A portocaval shunt caused the esophageal varices to subside, but the pulmonary arterial hypertension, resistant to corticotherapy, was rapidly fatal. In the case reported, the pulmonary arterial hypertension, independent of any parenchymatous lesion, was attributed to fibrosis of the arterial walls. The association of portal and pulmonary arterial hypertension with sarcoidosis is a very rare occurrence, and the pathogenesis of this association remains a debatable subject.

Adult↗
PubMed1979

[Chronic gastritis and intestinal metaplasia (author's transl)].

The diagnosis of chronic gastritis can be made from the macroscopic lesions seen on endoscopy, and the severity of the changes noted in the mucosa after biopsy under direct vision. Gastric intubation can also be used to confirm the pathological results. If the atrophied mucosa shows highly differentiated diffuse intestinal metaplasia, the examinations should be repeated at regular intervals, as they could herald the onset of malignant changes. The authors discovered 312 cases of intestinal metaplasia in 4 920 patients who had been gastroscoped in the Digestive Endoscopy Center of François-Moutier. A total of 157 of them, were noted to have very highly differentiated diffuse lesions, and 54 of these cases had at least yearly repeat gastroscopies. A diagnosis of intrinsic cancer was made in four patients, and this was confirmed by taking serial sections of the specimens removed.

Chronic Disease↗
PubMed1976

[Digestive lesions after abdominopelvic irradiation, in the treatment of cancers of the genital tract].

The authors report 15 cases collected over a few years on a gastroenterology unit, and emphasize the digestive complications occurring after pelvic or abdomino-pelvic irradiation for genital carcinoma. The rectum and pelvic colon are generally affected. The delays of onset after radiotherapy may reach or exceed several months. The vascular lesions, caused by ionising radiation, explain the tissue ischemia and, consequently the failure of local medical treatment. When severe hemorrhage or visceral perforation occur, surgery is necessary. However, sutures often break down on these insufficiently vascularised tissues and re-operation is always associated with a poor prognosis.

Aged↗
PubMed1976

[Caustic burn and adenocarcinoma of the esophagus].

Adenocarcinoma of the esophagus is found almost exclusively at the level of the cardia. It is exceptional to find it in the middle part of the esophagus in the absence of involvement of the cardia. In the long term, caustic burns of the esophagus may favour malignant degeneration. The latter is always squamous cell carcinoma. In our patient, a 28 year old man, a cylindrical carcinoma of the thoracic esophagus was detected four years after the ingestion of concentrated sodium hypochlorite. The caustic burn followed by carcinoma were of special significance in this case owing to the development of an adenocarcinoma.

Adult↗
PubMed1976

[Multiple angioleiomyomas of both lungs. Probable hamartomatous tumors. Very late death due to respiratory insufficiency].

Case presentation : Multiple tumor nodules in both lungs, identified by biopsy and necropsy, in a 48 year old woman, 8 years after radiological discovery ; death due to respiratory failure after long tolerance ; peculiar angio-leiomyomatous type pulmonary tumors. This purely pulmonary tumor disease is difficult to understand ; the most probable hypothesis envisaged is that of hamartomatosis ; comparison with certain general dysplastic disease is possible, and in particular Bourneville's disease and lymphangio-myomatosis.

Adult↗
PubMed1975

[Cystadenocarcinoma of the pancreas. Apropos of 2 cases].

The authors report two cases of cystadenocarcinoma of the pancreas and review the clinical, radiological and angiographic findings. The pathological study may be first disappointing, especially on frozen sections in the operating theater. The diagnosis depends essentially on the finding of an epithelial border which is difficult to demonstrate for it is often interrupted on one part of the circumference. Malignancy is suggested by the characteristics of the cells and the structural disorganisation. Total removal is necessary to avoid relapses, provided one removes neighbouring organs and all invaded lymph nodes. Cystadenomas and cystadeno-carcinomas are very rare tumours. The passage from one to the other seems inevitable. The necessity for surgery is thus absolute. However, if the malignant tumour is irremovable, an anastomosis between the cyst and the digestive tract may temporarily relieve the patient, especially as the course is sometimes rather slow.

Aged↗
PubMed1975

[Malformed tumoral hemangioma of the mediastinum. Apropos of 10 cases].

The malformed tumoral hemangioma of the mediastinum is highly specific tumoral entity, which must be distinguished from other varieties of hemangioma -- tumors arising in young subjects above all, and frequently large tumors of the mediastinum, whose radiological discovery leads to the most disturbing suppositions. It is however a benign tumor, most frequently surgically curable. Il is not so rare as it is said to be, at least in the child: it can be evoked in certain cases and even characterized sometimes. It is always better to avoid operative surprises in this connection, in this surgery of the mediastinum.

Adolescent↗