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F Cartier

Publications and source records attributed to F Cartier.

At least 19 recordsLinked to original sources
PubMed1991

Thrombotic thrombocytopenic purpura with the acquired immunodeficiency syndrome: a pathologically documented case report.

We report a patient with the acquired immunodeficiency syndrome (AIDS) in whom the acute onset of neurologic disorders and renal failure could be attributed to thrombotic microangiopathy. Clinical, biological, and pathological features were compatible with the diagnosis of thrombotic thrombocytopenic purpura (TTP). Such cases have been previously described, but histologically documented case reports are uncommon.

AIDS Dementia Complex↗
PubMed1990

[Nosocomial urinary tract infection].

Care for asepsis and the use of a closed drainage system reduce the risk of urinary tract infection with indwelling catheter. Beyond a few days, infection will still end to occur, earlier in female and diabetic patients. Local or systemic antimicrobials have neither prophylactic nor even therapeutic actual usefulness, as long as infection remain asymptomatic, which is by far the most frequent situation. Thus, repeated cultures of urine samples are needless. Treatment should be applied to symptomatic infection. The risk for infection is lower in case of intermittent catheterization, with the use of a penilex or a percutaneous bladder catheter. Some instrumental procedures of surgical techniques require short-term antimicrobial prophylaxis: prostatic endoscopic resection, transperineal or transrectal prostatic biopsy, percutaneous nephrolithotomy, prostatectomy, cystectomy, prostheses implantation.

Anti-Bacterial Agents↗
PubMed1990

[Urologic complications after 333 kidney transplantations].

26 urological complications were observed in 25 patients following 333 kidney transplantations. The low incidence of these complications (7.8%) is largely due to the systematic resort to the Leadbetter-Politano ureterovesical anastomosis, except in one case (uretero-ureterostomy due to the shortness of the graft). We recorded 9 urinary fistulae and 17 cases of ureteral obstruction. Urinary lithiasis was excluded from this work. Urinary fistulae occur almost only between the second week and the end of the first month. Ureteral obstructions occur relatively early (within 30 days in 14 cases and within the first 48 hours in 9 cases). Two grafts were lost (8% of complications, but 0.6% of the entire series), and one patient died following transplantectomy. In 10 of 26 cases (38.5%), the etiology of the urological complication was related to the harvesting technique (2 short ureters, 8 ischemic ureters).

Adolescent↗
PubMed1989

[Adult respiratory distress syndrome, a manifestation of severe pneumococcal infection].

A retrospective study analyzing the case notes of 49 hospitalized adults, either in intensive care (n = 26) or in thoracic medicine units (n = 23), for acute bacteriologically proven pneumococcal pneumonia based on samples obtained other than by sputum examination. The mortality was 54% in intensive care and 17% in the thoracic medicine unit. This significant difference may be explained in part by a respiratory distress syndrome in whom there were adequate criteria on admission for 7 patients in the intensive care group. Among these latter only one patient had had a splenectomy. The others did not have underlying disorders (three were chronic alcoholics); 7 patients were shocked on admission, four with a leukopenia less than 5,000/mm3 and six had a thrombocytopenia less than 100,000/mm3; finally 6 had a temperature of less than 38 degrees C. 7 patients died in less than four days (mean 2 days) in a clinical context of refractory hypoxemia. The significance of the respiratory distress syndrome is probably very different from the usual pneumonia; it seems rather to be an integration of the toxins induced by the pneumococcus. Its presentation can be particularly misleading as regards the diagnosis; the prescription of antibiotics once a diagnosis is obtained would seem insufficient by itself in this context to obtain a cure.

Adult↗
PubMed1988

[Pharmacokinetics of ceftriaxone in intensive care].

Pharmacokinetic parameters of ceftriaxone were studied on day 1 and 5 in 21 patients admitted in an ICU for severe infections. All patients received a single daily infusion of 2 g of ceftriaxone during 15 minutes. We have determined the ratio to the daily dose of serum ceftriaxone concentrations (peak level and trough level) and of areas under the curve. According to renal function and the existence of cholestasis, the results of our study showed: 1) In patients with creatinine clearance greater than 10 ml/mn and without cholestasis, a single daily infusion of 2 g ceftriaxone achieves therapeutic blood levels without any accumulation phenomenon. 2) In patients requiring hemodialysis without cholestasis, the period between two 2 g doses should be prolonged to 48 h. 3) Marked cholestasis and creatinine clearance greater than 10 ml/mn prolong the elimination half-life of ceftriaxone leading to an interval extension of the single dose of 2 g. Further investigations are needed in the latter situation.

Adult↗
PubMed1987

[What has become of preliminary transfusion protocols in kidney transplantation?].

Many studies have demonstrated that pretransplant blood transfusions improved cadaver kidney graft outcome. The nature and the frequency of transfusions-induced lymphocytotoxic antibodies depends of sex, previous pregnancies and kidney grafts, and transfusional patterns. This provoked immunisation is not a hindrance to beneficial effects of transfusions. Numerous reports have investigated the responsible mechanism for this effect. Controversial data concern the optimum number of blood units. In a previous prospective study in patients who received anti-lymphocyte globulins as part of immunosuppressive therapy, we have shown that a multiple transfusions policy does not give better results than only one. Recently, the beneficial effect of transfusions has been questioned, either entirely, or for particular patients according to age, sex, immunosuppressive treatment including cyclosporin or not. This leaded us to reassess benefits of transfusions.

Blood Transfusion↗
PubMed1986

Increase in blood plasma levels of boron and strontium in hemodialyzed patients.

Boron and strontium concentrations in blood plasma of controls and hemodialyzed patients from two Centers were determined by inductively coupled plasma emission spectrometry. Boron concentrations in blood plasma were respectively, in controls 2.6 +/- 0.9 mumol/l and in hemodialyzed patients 16.1 +/- 5.6 mumol/l before the dialysis session and 9.5 +/- 3.2 mumol/l at the end. The decrease in blood plasma during the dialysis was concomitant with an increase in the dialysis fluid (1.2 +/- 0.7 mumol/l at the beginning and 4.6 +/- 1.8 mumol/l at the end). Strontium concentrations in blood plasma were respectively, in controls 0.22 +/- 0.06 mumol/l and in hemodialyzed patients 0.62 +/- 0.24 mumol/l before the dialysis session and 0.64 +/- 0.14 mumol/l at the end. The mean concentration of strontium in the dialysis fluid was the same before (0.49 +/- 0.11 mumol/l) and after the dialysis session (0.49 +/- 0.10 mumol/l), but a transfer between plasma and dialysis fluid was shown by individual changes. Some considerations about these results are put forward but their possible clinical consequences are not yet known.

Adult↗
PubMed1986

Blood plasma fluoride in haemodialysed patients.

Blood plasma fluoride was determined in 15 chronic haemodialysed patients (60.2 +/- 7.2 yr old) before and after a 4-h dialysis using dialysates with very low fluoride level, and in two control groups, the first of 20 healthy younger subjects (45.9 +/- 3.4 yr old), the second of 8 healthy older subjects (69.1 +/- 6.8 y old). Before haemodialysis the fluoride concentration (1.31 +/- 0.31 mumol/l; 24.8 +/- 5.9 micrograms/l), was higher than in both control groups (0.35 +/- 0.16 mumol/l; 6.6 +/- 3.1 micrograms/l and 0.44 +/- 0.16 mumol/l 8.4 +/- 3.0 micrograms/l, respectively). During dialysis, the mean fluoride concentration fell to 0.94 +/- 0.26 mumol/l, remaining however, significantly higher than in control subjects. The use of fluoride-free dialysates seems to partially compensate the effect of renal impairment since plasma fluoride is only moderately increased in these patients.

Adult↗
PubMed1984

[Changes in the plasma and erythrocyte concentrations of rubidium in patients with renal failure].

Rubidium concentrations were measured by flame emission spectrophotometry in whole blood, plasma and red cells from male and female controls and from dialyzed and non-dialyzed patients of both sexes with chronic renal failure. Rubidium concentrations (mumol/l) in male and female controls respectively were: 2.29 +/- 0.29 and 1.96 +/- 0.46 in plasma: 36..79 +/- 5.90 and 30.19 +/- 6.11 in whole blood; 74.57 +/- 10.37 and 72.22 +/- 12.76 in erythrocytes. The red cell rubidium/plasma rubidium ratios were 32.6 in males and 38.3 in females. Compared with controls, dialyzed male and female patients showed, before dialysis, a decrease in rubidium concentrations of respectively -30% and -17% in plasma, -64% and -61% in whole blood, -40% and -33% in erythrocytes. A further decrease of 25% in rubidium plasma concentrations was observed after dialysis. Non dialyzed patients had an increase in plasma concentrations (+14% in males, +23% in females) and a decrease in erythrocyte concentrations (-16% in males, -20% in females) as compared with controls. Our data show that plasma and red cell rubidium concentrations are fairly constant and probably regulated in healthy subjects but vary considerably in patients with renal failure.

Adult↗
PubMed1984

Neurologic complications in a group of 86 bacterial endocarditis.

Criteria defined by von Reyn were applied to 86 cases of bacterial endocarditis. Neurologic complications (NC) were categorized according to Pruitt definitions. Neurologic accidents were observed in 48 cases. They were the first clinical manifestation in 20 patients. Neurologic events were of poor prognosis in BE, mortality increasing from 26% in patients without NC to 83% in patients with NC (P less than 0.01). Two factors affect the incidence of NC: first, the location of endocarditis with 76% of NC in mitral valve endocarditis compared with 37% in other cases (P less than 0.005); and second the infecting organism: 71% of NC in staphylococcus aureus endocarditis versus 45% in endocarditis with other bacteria (P less than 0.02). Cerebral embolism was the most common NC (25 cases) related to an occlusion of the middle cerebral artery in 21 cases with a fatal outcome in 19 patients. Other NC included 15 intracranial hemorrhages with the evidence of an aneurysm in 4 cases, 6 septic meningitis, 2 macroscopic abscesses, and 2 multiple microscopic abscesses. This study emphasizes the high rate and severity of NC in staphylococcal mitral endocarditis despite antibiotic therapy and supports early surgery in this group of bacterial endocarditis.

Adolescent↗