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Biomedical subjects

F Catapano

Publications and source records attributed to F Catapano.

32 records · Page 2Linked to original sources
PubMed1991

[Effects of nimodipine on mental deterioration in subjects with chronic cerebrovascular pathology].

In order to assess the efficacy of Nimodipine against a polymorphous pathology, such as chronic cerebrovascular insufficiency, the authors studied 96 subjects affected by chronic cerebrovascular diseases aged between 65 and 85 years old. The various symptoms were evaluated individually using tests and subjects were then divided into two groups on the basis of overall results. All subjects were followed for six months and then reassessed using the above-mentioned tests at the end of the study. From results obtained, it appears that Nimodipine is a useful tool for controlling the most common symptoms associated with mental deterioration in subjects affected by chronic cerebrovascular disorders.

Aged↗
PubMed1990

Dexamethasone suppression test in patients with primary obsessive-compulsive disorder and in healthy controls.

The dexamethasone suppression test (DST) was performed in 18 patients (11 women and 7 men) who met the DSM III-R criteria for obsessive-compulsive disorders (OCD), and in 20 healthy volunteers (12 women and 8 men). At 4.00 p.m., following dexamethasone administration, 5 patients (27.7%) and 1 healthy subject (5%) displayed plasma cortisol values well above the cut-off value of 50 ng/dl. A significantly different sex ratio was observed between suppressor and nonsuppressor patients with OCD (chi 2 = 4.40, p less than 0.03), because all nonsuppressor patients were male. Compared to the suppressors, nonsuppressor patients with OCD did not differ in any of the clinical and demographic variables investigated. Moreover, in our patient sample, the mean +/- SD total Hamilton Depression Rating Score (HDRS) was 14.8 +/- 2.5, and none of the nonsuppressors with OCD had a total HDRS greater than 17. These data suggest that a subgroup of OCD patients, particularly males, may escape the DST independently from the coexistence of depressive features.

Adolescent↗
PubMed1990

Depression and cerebral stroke.

Behavioral and psychological changes following cerebrovascular pathology have long been known. Depression, often severe and long-lasting, is a common and often unrecognized component of stroke. Although many of the clinical characteristics of poststroke depression have been reported in the literature for years, systematic studies of the frequency, course, relationship to lesion location, and response to treatment have only recently been undertaken. In this review, the authors briefly examine these various aspects of poststroke depression.

Cerebrovascular Disorders↗
PubMed1984

[Effect of street noise on blood catecholamines, cyclic AMP and various cardiovascular and metabolic functions in a group of subjects with untreated essential hypertension].

The effect of road noise on blood catecholamines, cAMP and certain cardiovascular and metabolic parameters was studied in a group of young untreated essential hypertensives. It was found that the 10' stimulus increased both systolic and diastolic pressure values. Blood catecholamines rose only after 5'. The most significant increase was in adrenaline as opposed to noradrenaline and dopamine. Significant changes were noted in cAMP and triacylglycerols (10' and 15' after commencement of the stimulus respectively). Comparison with previous results in normotensives suggested that the catecholamine response to stress is primarily alpha-receptorial when blood pressure is normal and beta-adrenergic in hypertension.

Adult↗
PubMed1984

[Myxoma of the left atrium. General considerations and description of a case].

A case of left atrial myxoma is described. The neoplasia was observed in a female with no previous rheumatic history in whom cardiopathy was diagnosed only a few months before hospitalisation. The rapid and erratic course of the cardiopathy, the fact that changes of posture modified objective symptoms, the presence of dyspnoea and peripheral microembolisms were all clinical indicators of a possible myxoma, later confirmed by echography and cardiac catheterism. The anatomical and functional characteristics of myxomas are also discussed.

Adult↗
PubMed1984

[Effects of street noise on plasma catecholamines, cyclic AMP and various cardiovascular and metabolic functions in a group of normal subjects].

Exposure to traffic noise for ten minutes increased diastolic pressure without affecting systolic pressure and heart rate. Plasma catecholamine levels were enhanced only five minutes after noise stimulation. Noradrenaline increased more significantly than dopamine and adrenaline. No changes in plasma cAMP levels and hematochemical parameters ( cholesterol , glucose, triglycerides , uric acids) were observed. Data suggest that traffic noise can be considered a stress-full stimulus and its effect on diastolic pressure can be correlated to alpha-receptor stimulation.

Adult↗
PubMed1984

[Rupture of the chordae tendineae and mitral prolapse. General considerations and description of a case].

A severe case of acute mitral insufficiency caused by a ruptured tendinous cord is described. The subject had an unrecognised mitral prolapse and had been suffering from tachycardia for years when an attack of pulmonary oedema occurred some days after apparently well tolerated exertion. The phenomena behind the event are discussed with particular reference to the mechanisms, closure and distribution of prolapses in so-called mixamatosic degeneration of the valve. The importance of body position and exertion in the creation and deterioration of prolapses is also emphasised.

Acute Disease↗
PubMed1976

[Isoproterenol in the emergency treatment of cardiac stimulus conduction].

Continuous infusion with isoproterenol (mean dose 2 mug/min) was carried out for periods of a few hours to a few days in 22 patients recurrent Adams-Stokes syncope. In all cases, an improvement leading to or in the direction of physiological cardio-circulatory conditions was noted. Undesired side-effects foreseeable as the result of beta-adrenergic stimulation were not observed. Isoproterenol is more active than metaproterenol and is to be preferred on this account. It is indicated in Adams-Stokes crises due to conduction disturbances when pacemakers cannot or should not be fitted, or as a prelude to their application.

Adams-Stokes Syndrome↗
PubMedDate not supplied

Insight and resistance in patients with obsessive-compulsive disorder.

The aim of this study was to evaluate the degree of insight and resistance in a sample of obsessive-compulsive patients, and the predictive value of poor insight with respect to response to treatment with serotonin reuptake inhibitors (SRIs). Ninety-three patients fulfilling DSM-IV criteria for obsessive-compulsive disorder were evaluated. Seventy patients were treated with an SRI in a 24-week open-label trial. Sixteen percent of the patients did not recognize obsessions and compulsions as unreasonable or senseless. Fifty-two percent of the patients did not try to resist, 72% had little or no control over obsessions, and 64% were not able to exercise an effective control over compulsions. Patients with poor insight had a greater severity of obsessive-compulsive symptoms, a higher rate of schizophrenia spectrum disorders in their first-degree relatives and a higher frequency of a history of psychiatric disorders during childhood. Fifty-two percent of the patients with normal insight responded to SRIs, whereas none of the patients with poor insight were found to be responders. These results suggest the utility of the assessment of insight and resistance in obsessive-compulsive patients, also for the prediction of response to treatment with SRIs.

Adolescent↗
PubMedDate not supplied

[Acute and chronic effects of standard hemodialysis and soft hemodiafiltration on interdialytic serum phosphate levels].

INTRODUCTION: The dialytic management of hyper-phosphoremia, which is inadequate because of insufficient intra-dialytic removal of phosphate (P), is further limited by PDR-P, i.e. the significant increase in serum P levels during the early postdialytic period. Patients and methods. To investigate the effects of enhanced P removal by haemodiafiltration on the inter-dialytic phosphoremia, we studied 12 uremic patients that were switched, with cross-over randomised modality, to a single session of standard hemodialysis (HD) and hemodiafiltration (HDF) (Acute Study). Blood samples were obtained before the treatment, at the end (T0), after 30, 60, 90 and 120 minutes, and at 24, 48 and 68 hours. During both dialytic treatments the whole effluent dialysate was collected to evaluate the intradialytic removal of P. Thereafter, patients were randomised to receive either HD or HDF for three months, in the presence of constantly similar Kt/V, food intake and dose of phosphate binder (Chronic Study). RESULTS: Acute Study. Compared to HD, P removal in HDF was about 44% greater in the presence of identical predialytic P levels (6.0+/-0.2 and 5.9+/-0.4 mg/dl) and Kt/V (1.35+/-0.06 and 1.34+/-0.05); however, the inter-dialytic decline of serum P levels did not differ (-50+/-3% versus -42+/-3%, p=0.098). In HDF, PDR-P was faster (30 min versus 90 min) and better (at T120: +69+/-6% versus +31+/-4%, p<0.001). The higher P levels were maintained throughout the inter-dialytic period whereas Ca x P changed in parallel. Chronic Study. During the three months, pre-dialytic serum P diminished in HDF (from 5.8+/-0.2 to 4.4+/-0.3 mg/dl, p<0.05), while it remained unchanged in HD. A similar pattern of changes was detected in Ca x P. CONCLUSIONS: Enhancement of P removal, acutely amplifies the extent of PDR-P, but allows better control of Ca-P homeostasis in the medium term. This effect is likely to be dependent on the enhanced mobilisation of phosphate from a deep compartment.

Adult↗