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Biomedical subjects

F Cattin

Publications and source records attributed to F Cattin.

At least 55 records · Page 3Linked to original sources

Extraforaminal lumbar disc herniations: CT demonstration of Sharpey's fibers avulsion.

Forty-seven extraforaminal lumbar disc herniations (EFLDH) accounting for 7% of all lumbar disc herniations encountered during the same period of time were reviewed. L3-L4 or L4-L5 disc was involved in 89% of the cases giving rise to a L3 or L4 nerve root compression. An abnormal motion of lateral bending with rotation of the trunk was found retrospectively in 60% of the patients. In 53% of all EFLDH a bony avulsion of the vertebral end-plate facing the herniation was demonstrated at the site of attachment of Sharpey's fibers. This study suggests that this previously undescribed bony change witnesses a special injury of the spine responsible for most EFLDH.

Adult↗

Hypothalamic-pituitary region: computed tomography imaging.

High resolution CT with dynamic scanning, demonstrating the pituitary tuft, the pituitary enhancement and the related vascular structures, is of major benefit for the diagnosis of pituitary lesions. Perfection of examination techniques is essential for accurate application of the modality to detect subtle diagnostic signs. A good knowledge of normal anatomy and variants of the sella turcica and pituitary gland permits one to avoid most of the misdiagnoses. Since the CT findings are often non-specific to tissues, clinical endocrinological correlation is essential. The technique also allows consistent assessment of the extent of the disease to permit better treatment planning and effective follow-up of patients after therapy.

Cavernous Sinus↗

Neuroblastoma-like epidural localization in non-Hodgkin's lymphoma.

We report a case of non-Hodgkin's lymphoma with CNS involvement confined to the epidural space causing cranial suture diastasis. Cerebrospinal fluid and bone marrow were normal. Two cases only of cranial epidural lymphoma have been reported in the literature; in both cases, the leptomeninges were also involved but without suture diastasis.

Adolescent↗

MR imaging of the cavernous sinus: value of spin echo and gradient recalled echo images.

A detailed evaluation of the MR appearance of the pituitary gland-cavernous sinus junction has not been described. In a series of coronal T1-weighted spin echo images without and with IV gadolinium, we noted the variable size and signal intensity of cavernous venous spaces adjacent to the pituitary gland and the inconsistent visualization of the dural membrane just lateral to the gland. Correlation of coronal T1-weighted spin echo and gradient recalled echo images (the latter with high-signal-intensity vascular structures) proved to be an effective means of identifying cavernous venous spaces, connective tissue and cranial nerves, and the lateral margins of the pituitary gland, and of differentiating tumor tissue from cavernous venous spaces. Further work is needed to develop criteria to distinguish cavernous sinus compression from actual tumor invasion.

Adenoma↗

Wallerian degeneration of the descending tracts. CT and MRI features of the brain stem.

The authors have studied by CT brain infarcts of different ages in 16 patients, two of whom were also examined by MRI. The early and CT signs of wallerian degeneration of the descending tracts within the brain stem are described. Three cases of crossed cerebellar atrophy are reported; in one of them, the cerebral lesion had been present for less than 8 years. The physiopathology of pontine hemiatrophy and crossed cerebellar atrophy is discussed.

Adolescent↗

Computed tomographic demonstration of the posterior pituitary.

From a series of 700 thin, axial, contrast-enhanced CT scans of the sellar region, the posterior lobe of the pituitary was studied. Empty sellae and pituitary lesions larger than 8 mm in diameter were excluded from the study. Of the 320 remaining axial contrast-enhanced CT scans, the posterior lobe of the pituitary was apparent in 124 (39%) as an oval lucency 3-4 mm thick, located medially or paramedially just in front of the dorsum sellae. Normally, the anterior limit of the posterior lobe is always regularly convex forward, but in the presence of a microadenoma of the anterior lobe it may be compressed. The lesser enhancement of the posterior lobe probably correlates with the different volumes of the interstitial spaces in the anterior and in the posterior lobes. The normal picture of the posterior lobe of the pituitary must not be confused with a posteriorly located microadenoma.

Humans↗

Computed tomography of the sellar spine.

The authors report the CT scan findings in a case of sellar spine. This osseous spine which arises in the midline of the anterior aspect of the dorsum sellae and is directed toward the center of the sella turcica has already been described on specimens and on plain films but never on CT scans. The CT scan findings confirm the normal appearance of the surrounding structures.

Bone Diseases↗

CT follow-up of microprolactinomas during bromocriptine-induced pregnancy.

In the last few years complete or partial regression of prolactinomas has been demonstrated in nonpregnant women treated by bromocriptine. Thus bromocriptine therapy appears as an attractive alternative to surgery for management of infertility related to hyperprolactinemia. However, numerous reports emphasized the possibility of an excessive growth of the pituitary adenoma with visual field defects during the last 3 months of pregnancy. To avoid these complications, the authors followed with serial CT scans the growth of microprolactinoma at the 5th or 6th month of pregnancy. Among six pregnant women, one patient presented a marked upward extension of the adenoma. Bromocriptine was then reintroduced and the effectiveness in reducing tumor growth was proved by CT scan at the 7th month. Regarding low risk of using intravenous iodinated contrast medium in pregnant women and of fetal radiation damage, the authors emphasize the value of CT in the follow-up of bromocriptine-induced pregnancies.

Adult↗

Dynamic computed tomography of the pituitary gland: the "tuft sign".

Diagnosis of an intrasellar pituitary microadenoma by CT may be difficult if the only finding is a small defect in enhancement. The diagnosis can be facilitated by dynamic CT of the pituitary gland in the coronal plane. This method permits visualization of the capillary bed of the pituitary, whose displacement ("tuft sign") could be an indication of the presence of a microadenoma.

Adenoma↗

Computed tomographic demonstration of the effects of bromocriptine on pituitary microadenoma size.

A group of 17 strictly intrasellar prolactin-secreting pituitary adenomas between 2 and 9 mm in size was examined by computed tomography before and after bromocriptine therapy of 3 months to 1 year duration. These findings were compared with clinical and biological data. Bromocriptine therapy was effective clinically and biologically in 14 of the 17 cases. Of the 15 intrasellar adenomas in nonpregnant patients treated with bromocriptine, six disappeared completely with normalization of the pituitary appearance, five decreased approximately 50% in volume (three showed an increase in density, two a decrease), and four remained unchanged in size (two showed increased density, two showed very low densities).

Adenoma↗

Dynamic CT of the laterosellar extradural venous spaces.

We evaluated the ability of dynamic CT scanning to accurately demonstrate the laterosellar extradural venous spaces. Careful examination of 680 consecutive patients with this technique has permitted us to describe four main venous groups: the veins of the lateral wall (present in 98% of cases), the vein of the inferolateral group located beneath cranial nerve VI (present in 92% of cases), the medial vein located between the internal carotid artery and the pituitary gland (present in 20-30% of cases), and the vein of the carotid sulcus located between the intracavernous internal carotid artery and the lateral wall of the sphenoid bone (present in 65% of cases). The vein of the carotid sulcus is absent only when the internal carotid artery lies close to the sphenoid bone. In 12 patients with suspected cavernous sinus invasion, dynamic CT scanning demonstrated obliteration of the vein of the carotid sulcus. In five patients with huge tumors of the temporal region, dynamic CT scanning of the cavernous sinus permitted demonstration of normal laterosellar extradural venous spaces, thus permitting exclusion of intracavernous sinus invasion. We believe dynamic CT is the imaging technique best suited for studying the laterosellar extradural venous spaces. Its spatial resolution and dynamic capacity make it superior to MR, and it should be the first procedure when invasion of the cavernous sinus by a pituitary tumor is suspected.

Adenoma↗