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Biomedical subjects

F Collet

Publications and source records attributed to F Collet.

30 records · Page 2Linked to original sources

[Percutaneous aortic valvuloplasty by trans-septal approach].

Aortic valvuloplasty has recently been introduced in the treatment of some cases of aortic stenosis. In the case reported here, the aortic orifice was so difficult to traverse by the retrograde route that the obstacle was approached by trans-septal catheterization. The aortic area, initially estimated at 0.25 cm2, increased to 0.82 cm2 at the end of the examination. However, additional dilatation by the retrograde route was necessary, using a catheter 25 mm in diameter.

Angioplasty, Balloon↗

[Electro-mechanical dissociation concomitant with myocardial reperfusion in the acute phase of myocardial infarction].

An unusual case of transient electro-mechanical dissociation concomitant with myocardial reperfusion is reported. The patient had myocardial infarction caused by occlusion of the middle anterior interventricular artery relieved by injection of urokinase and plasminogen in situ. The dissociation could be documented by simultaneous ECG recording on 3 leads and direct intravascular recording of femoral arterial pressure, the patency of that artery, and its maintenance, being demonstrated by angiography. This clinical case can be added to the list of events which occur during reperfusion of the myocardium after prolonged ischaemia. Its mechanisms, so far, are purely conjectural.

Blood Pressure↗

[Evaluation of the prognosis of mitral valve prolapse].

It is not easy to evaluate the prognosis of mitral valve prolapse. First of all, a positive diagnosis is difficult: the clinical insufficiencies are ill-compensated by sonocardiography as it is less reliable than expected; the very existence of the "mitral valve prolapse" described by Barlow is being challenged. Secondly, the most severe complications of mitral prolapse are rare, with respect to its frequency. Some complications are currently well defined. Thus, severe mitral insufficiency, leading to valve replacement, affects elderly men more than young women, although the pathological lesions correspond to the same disease. Endocarditis is rare and only occurs when there is an audible murmur. Rhythm disorders are varied, with however, frequent junction tachycardias and a marked influence of catecholamines, which may explain the clinical effectiveness of beta-blockers. Unfortunately, severe complications are not as well known. Thus, the risk of sudden death and cerebral vascular accident cannot be figured out from large statistical studies. Only studies of some so called "risk" sub-groups, should allow a better knowledge of these two complications and a more effective prevention.

Humans↗

Long-term follow-up of mitral valve prolapse and latent tetany. Preliminary data.

The association between idiopathic mitral valve prolapse (MVP) and latent tetany (LT) is common, as shown in our previous studies on adults and children. On the basis of our experience with the effects of magnesium salts and/or beta-blockers on the symptoms of such patients, we tried to determine whether this therapy could also modify the left ventricular hyperkinesia (LVH) constantly associated with MVP. After showing the failure of short-term therapy (1-3 months), we found 12 cases treated for more than 1 year, having MVP, LVH and LT. The mean duration of this continuous therapy was 36.5 months (range 12-72 months). 5 men and 7 women (mean age 49; range 28-70) received magnesium salts (pyrrolidone carboxylate 4.5 g/day, lactate 3 g/day) either alone (2 cases) or associated with a beta-blocker (atenolol 100 mg/day, acebutolol 200-400 mg/day, propranolol, 40-160 mg/day; 10 cases). The erythrocyte magnesium was measured before, during and after therapy. All these 12 patients had repeat echocardiography at the end of the treatment. MVP was still present, as was LVH, in 50% of them. Mean erythrocyte magnesium was below the normal range before therapy (43 +/- 6.3 mg/l) and in the normal range after therapy (50.8 +/- 7 mg/l). But no relationship was found between the increase in erythrocyte magnesium and the disappearance or persistence of MVP and LVH. Therefore, the improvement of the patients' clinical status was not always followed by a significant change in erythrocyte magnesium values and in echocardiographic findings, even after long-term therapy.

Adrenergic beta-Antagonists↗

[Tricuspid endocarditis with right-left shunt in the atrium].

A case of tricuspid regurgitation due to endocarditis causing a right-to-left shunt through a patent foramen ovale is reported. Tricuspid valve endocarditis occurred after septic abortion and caused valvular regurgitation with dyspnea and cyanosis. The diagnosis was made by echocardiography and the finding of peripheral arterial desaturation, and it was confirmed at surgery. The physiopathology of these right-to-left shunts is the same as that already described during traumatic tricuspid regurgitation: reopening of the foramen ovale by the right atrial dilatation and ventricularisation of right atrial pressures. The presence of a shunt is an indication for surgery.

Abortion, Spontaneous↗

Selective coronary arteriography by percutaneous transaxillary approach.

Coronary angiography by the percutaneous femoral approach is widely used. This technique is potentially dangerous or impossible in patients with advanced arterial disease of the lower limbs, whether or not surgically treated. In these cases, percutaneous left or right axillary approach is an alternative to brachial approach. In this article, we report our multicenter experience involving 120 patients. The left axillary artery was used in 94 cases (78%) and the right in 26 cases (22%). We used performed coronary catheters usually associated with the femoral approach. The left axillary artery was used preferentially since this avoids catheterization of the innominated trunk and allows easier catheterization of the coronary ostia and aortic ends of aorto-coronary bypass grafts. The routine use of a sheath (arterial introducer) avoided arterial compression during catheterization, prevented hemorrhagic suffusion when the catheters were exchanged, and reduced the risk of thrombosis or laceration of the axillary artery. There were no failures in the catheterization of the axillary artery and no complication was observed during or after the procedure. Axillary percutaneous technique appears to have the following advantages over the brachial arteriotomy: 1) Investigation time is equivalent to the time needed for the femoral percutaneous approach. 2) There is the possibility of lateral and simultaneous bi-plane angiograms. 3) Arterial puncture is preferable to arteriotomy. The axillary approach could also be used for percutaneous transluminal coronary angioplasty.

Adult↗

[Acute occlusion of the renal artery caused by an embolism of cardiac origin. Treatment by in situ thrombolysis].

An intra-arterial infusion of streptokinase successfully dissolved a large thrombus of the renal artery in a 54-year old male patient with old-standing mitral stenosis. This case illustrates the effectiveness of fibrinolysis in situ. This method provides complete arterial recanalization and preserves the renal function, thus enabling surgical embolectomy to be performed.

Acute Disease↗

[Behçet's disease and cardiovascular pathology].

Behçet's syndrome appears in different localisations. Some of them were at the source of the initial description of the disease and are therefore well known. However, cardiovascular localisations were discovered later on and are worthy of detail. They may enable retrospective diagnosis and are an evolutive turning point in this still mysterious disease.

Behcet Syndrome↗