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Biomedical subjects

F Colombo

Publications and source records attributed to F Colombo.

At least 163 records · Page 9Linked to original sources
PubMed1982

Long-term occupational risk of rare-earth pneumoconiosis. A case report as investigated by neutron activation analysis.

A case of rare-earth (RE) pneumoconiosis is described and discussed. A man working in a lithographic laboratory as a photoengraver, and exposed to the smoke of cored carbon arc lamps over a period of 46 years developed an interstitial pneumoconiosis. Neutron activation analysis (NAA) of eight rare-earths (La, Ce, Nd, Sm, Eu, Tb, Yb and Lu) in lung and lymph node biopsies showed an abnormally high amount of these elements in comparison to the corresponding values of 11 autopsied for unexposed subjects. The estimated radiological dose due to the inhalation of natural thorium, as calculated from NAA of thorium in the biopsies, tends to exclude the effect of ionizing radiation in the pathogenesis of lung fibrosis. Effects of other potential pathogenetic agents such as coal or heavy metal dusts, other than RE, irritative agents such as nitrous and hydrofluoric vapours originated during the photoengraving process, are also discussed. The findings strongly suggest that a relationship exists between the pneumoconiosis diagnosed and the occupational exposure to rare-earth dusts calling attention to proposals for maximum permissible concentration limits of occupational exposure to RE in air.

Animals↗
PubMed1982

Platelet function in rheumatoid arthritis.

Platelet function tests were evaluated in 20 patients with rheumatoid arthritis (RA), 9 of whom displayed thrombocytosis (greater than 400,000 platelets/microliter). Most patients had an enhanced sensitivity to collagen and epinephrine induced aggregation, as compared with a reference group. In contrast, malondialdehyde (MDA) production, an index of platelet arachidonic acid metabolism, was in the normal range for all the patients except 3, who were LE phenomenon positive. The hypersensitivity of platelets to aggregating stimuli was particularly marked in thrombocytotic patients, who also showed the most striking biochemical and clinical abnormality. These findings indicate the crucial role of platelets in the development and self-sustaining of RA.

Adult↗
PubMed1982

[Truncal vagotomy and cholelithiasis].

A group of 50 patients with total vagotomy plus pylorolasty are studied with pre and postoperative cholecystography in a four years follow-up. 50 patients with parietal cell vagotomy (selective vagotomy) served as control group. The AA. study the correlation of gallbladder dilatation with gallstones formation after total vagotomy. On the contrary parietal cell vagotomy prevents these dysfunctions.

Cholelithiasis↗
PubMed1981

A new method for utilizing CT data in stereotactic surgery: measurement and transformation technique.

The proposed system is essentially based on the definition of a coordinate system, rigidly connected with the skull, by the introduction of three reference X-ray opaque points, secured into the bone of the skull. Target and reference points CT coordinates are given by the image display console. The three reference points are also identified on stereoradiographs, and their actual stereotactic coordinates are calculated by a geometrical approach which takes into account radiological distortion. A programmed computer links the target, identified on tomograms, to the three points system and calculates its stereotactic coordinates.

Humans↗
PubMed1981

Spinal surgery for spasticity (46 cases).

The authors report their experiences in the surgical treatment of spastic syndromes by operations on the spinal cord and nerve roots. In the authors' neurosurgical department 20 lumbar myelotomies, 19 posterior selective lumbar rhizotomies, 2 complete posterior lumbar rhizotomies, 4 anterior lumbar rhizotomies and five posterior cervical rhizotomies were performed. Clinical results can be considered good on the whole. There was no mortality and no major complication in the entire series. The effect of selective posterior lumbar rhizotomy on the evolution of cerebropathic spastic paraparesis was particularly impressive. Six of 46 patients experienced a late recurrence of spasticity, but they all had good results after a further operation. The particular criteria for selection of each surgical procedure are discussed and related to the aetiology and clinical picture of the spastic syndrome.

Adolescent↗
PubMed1981

[Juvenile hypertension. Results of a study in high school in Milan (author's transl)].

Blood pressure has been measured in a cohort of 2300 high school students of Milan (14-15 years old) for two years on end. The prevalence of "borderline hypertension" was 11.5% at the first examination and 8.5% at the second. The values of blood pressure were decreased, in every measurement, after a year from the initial screening especially in "borderline hypertensives". This study has confirmed that the "borderline hypertension" in subjects 14-15 aged is a transient phenomenon, but the incidence of "stable hypertension" as been found higher significantly in "borderline hypertensives" than normotensives. The results are discussed.

Adolescent↗
PubMed1980

The broken clip.

A case of a broken clip demonstrated by radiography is presented. As angiography showed no filling of the aneurysm, further operation was not considered necessary. The cause of the fracturing of the clip remains unknown.

Female↗
PubMed1980

[Arterial hypertension caused by ingestion of licorice].

The Authors present a case of licorice-sustained hypertension in a young man. blood and urine tests revealed: hypokaliemia with hyperkaliuria, suppressed plasmatic renin activity, absent urinary aldosterone. A symmetric left ventricular hypertrophy was detectable at the echocardiogram. Five months after the interruption of licorice ingestion the valves of systemic blood pressure were normal and the haematochemical investigations were also within normal limits. An echocardiogram revealed the disappearance of the signs of left ventricular hypertrophy and myocardial mass was reduced of about 40%. The usefulness of an echocardiographic examination, to evaluate hypertensive cardiomyopathy, is stressed.

Adult↗