PubMed HealthSearch

Biomedical subjects

F Contreras

Publications and source records attributed to F Contreras.

At least 55 records · Page 3Linked to original sources

Malignant rhabdoid tumor of the tongue. A case report with immunohistochemical and ultrastructural findings.

An extrarenal malignant rhabdoid tumor of the tongue in a 10-day-old boy is described. The tumor produced severe respiratory distress and had an aggressive clinical course. The patient died 17 days after the initial diagnosis. The tumor was mostly composed of poorly differentiated, round, polygonal or elongated cells. Ultrastructural examination showed intracytoplasmic filamentous inclusions in many of the cells. The cytoplasm was diffusely positive to anti-vimentin antibodies with focal, scarce positivity to anti-keratin antibodies. To the best of our knowledge, this is the first reported case of malignant rhabdoid tumor of the oral cavity.

Cell Nucleus

Mycobacterium chelonei peritonitis due to hematogenous dissemination in a continuous ambulatory peritoneal dialysis patient.

Renal failure patients have been found to have a special susceptibility to Mycobacterium infections. In patients undergoing peritoneal dialysis, Mycobacterium chelonei peritonitis, due to penetration through the peritoneal catheter lumen, has been described. In our report, we described a case of disseminated M chelonei infection that began in a Thomas hemodialysis prosthesis and finally resulted in peritonitis of hematogenous origin. The diagnostic and therapeutic peculiarities are discussed.

Adult

Uterine intravascular leiomyomatosis: an update and report of seven cases.

A clinicopathological study of seven cases of intravascular leiomyomatosis (IVL) was performed. The patients' ages ranged from 29 to 80 and all cases were associated with uterine leiomyomas. The intravascular extension involved preferentially uterine vessels, although the adnexa were also affected. Microscopically, the intravascular tumors resembled the primary leiomyomas. Mitotic count was low and never exceeded 3 per 10 high-power fields. Thick venous vessels, sometimes with thrombosis, were a conspicuous marker in intravascular locations. Necrosis and hemorrhage were found in four cases. Epithelioid IVL was found in one instance associated with a lipid cell tumor of the ovary. This series supports, for most cases, the notion of an origin from a preexisting leiomyoma. A review of treatment, prognosis, and histogenesis of IVL is performed.

Adnexa Uteri

The effect of copper ions in vivo on specific hormonal endometrial receptors.

A comparative randomized study was made of three intrauterine contraceptive devices: the Nova-T, MLCu250 Short and MLCu375. An endometrial biopsy was performed on the 25th day of the menstrual cycle before and after IUD insertion. The tissue obtained was analyzed to determine estrogen and progesterone receptor concentration and endometrial morphology patterns in IUD users. Both estrogen and progesterone receptors decreased proportionally to the increased amount of copper in the IUD. The histologic study showed changes in endometria relative to the amount of copper, but these changes were transitory and disappeared after a year of IUD use.

Adult

[Fetal rhabdomyomatous nephroblastoma: study of 2 cases and review of the literature].

Report of two cases of Fetal Rhabdomyomatous Nephroblastoma, a cytodifferentiated variant of Wilms' tumor. The incidence of this rare variant is of 2.10% in our material (88 nephroblastomas in a sixteen years period). The patients were ten months and two years old. Bilateral tumors were discovered in both patients. Preoperative radiotherapy was given but no reduction of the tumors size was obtained. Microscopically, benign looking striated muscle is the predominant component of the tumors, with scare foci of epithelial elements. The low age of presentation, high incidence of bilaterality and the peculiar intrapelvic renal growth are three relevant characteristics in the 35 cases previously reported as well as in these two new cases, that distinguish Fetal Rhabdomyomatous Nephroblastoma from conventional Wilms' tumor.

Female

[Use of the peroxidase-antiperoxidase technic in cytologic smears in pemphigus vulgaris].

The diagnosis of pemphigus is presently based on the correlation of clinical, histological, and direct and indirect immunofluorescent data. This article has presented the result of a study of cytological smears, taken from cutaneous lesions on five patients previously diagnosed as having pemphigus vulgaris, treated with the peroxidase-antiperoxidase technique which demonstrated a constant pattern of acntholitic cells surrounded by IgG. The authors belive that this means of study combines a high level of reliability and specificity with advantage of enabling the use of material that can be stored for a long time without special conditions, does not require biopsy and can supply data of great value for the diagnosis of this condition.

Evaluation Studies as Topic

[The PTFE plastic prosthesis as an arterial replacement: experiences over a 5-year period].

Unilateral iliac femoral reconstructions with PTFE are yielding good results-similar to those with Dacron, with patency rates of 75, 67, and 65% at 1, 2 and 3 years, respectively (Kaplan-Meier). PTFE has additional advantages compared with other materials: a) no need of preclotting; b) smooth inner surface-easy thrombectomy in case of thrombosis and c) good handling characteristics. In view of the above-mentioned facts PTFE can be recommended without restriction for unilateral pelvic reconstructions. The functional early results of bilateral aorto-femoral Goretex-Y bifurcation grafts in 50 cases after 2 years are encouraging. Long-term results are still pending. Reports of other groups using this material as aorto-bifemoral substitute are not yet available. The functional results with PTFE for femoro-popliteal grafts are not satisfactory: 35% after 2.5 years. Extra-anatomical bypasses yielded 70% one-year functioning rate. Especially the ring-or spiral-armoured PTFE grafts seem to be suitable for these reconstruction procedures.

Aged

[Clinical aspects and therapy of congenital cystic livers].

Thirty patients with congenital cystic disease of the liver are reported. Expansion with pain, jaundice, cholangitis and suspicion of malignancy are indications for surgical intervention. Operation is chosen according to localization, size, quantity of cysts and their fluid content. Resection, fenestration, punction, anastomosis and hemihepatectomy were performed. Postoperative mortality was about 3%, prognosis is well, but worsened by associated diseases like polycystic kidneys or intramural aneurysms.

Cysts

Postoperative assessment of below-knee bypass grafts.

Our results seem to demonstrate that, even when healthy or arteriosclerotic arteries tolerate knee flexion without any impairment of blood flow, all bypass materials, to a certain extent, have a tendency toward morphologic changes, such as kinking, looping, stenosis and decrease of peripheral blood flow. Reocclusion in below-knee reconstruction, which cannot be explained by poor outflow situation or technical faults, might be related to the graft material used as well as hemodynamic changes caused by flexion of the knee joint. With the use of ASV grafts, these changes are minimal and of little or no clinical importance; when HUV is used, these changes are more distinctive and might, in some instances, be the cause of reocclusion. This could explain the difference in the late results with the use of ASV or HUV. The results of reinforced PTFE still await evaluation. However, it should be kept in mind that the results in addition to the already mentioned influences are also caused by neointima proliferation and progression of the disease.

Aged