[Thyroiditis in primary care: suspected postpartum thyroiditis].
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Biomedical subjects
Publications and source records attributed to F Cuadrado.
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The authors report 200 examinations and discuss the role of radio-isotope scans of the pancreas with electronic subtraction of the liver image in acute and chronic pancreatitis. As an emergency, the examination is of definite diagnostic value, the absence of fixation with a suggestive clinical context, is strong evidence of pancreatic disease and normal uptake eliminates the latter. On the other hand, in painful syndromes in which chronic pancreatitis is suggested, the diagnostic interest is very limited for the low uptake on radio-isotope scan occurs at a late stage and is not specific. Radio-isotope scans are worth a place in exploration of the pancreas in acute pancreatitis.
A double-blind, prospective, randomized study was performed with 90 patients undergoing colorectal surgery, to ascertain the prophylactic effect of three different parenteral antibiotic programs. The patients were divided into three groups. The patients in group 1 received 80 mg Gentamycin and 600 mg Lincomycin intramuscularly, two hours preoperatively, and every eight hours postoperatively for three days. In group 2, the treatment was similar to group 1 but the Lincomycin was replaced by 600 mg Clindamycin. In Group 3, the treatment was also similar to group 1, but 500 mg Metronidazole given over 20 minutes replaced the Lincomycin. The present study, the first comparing three antianaerobic antibiotics and an aminoglycoside in the prophylaxis of infection in colorectal surgery, shows certain clinical and socioeconomic benefits, although not statistically significant to be found in the group 3 program (Gentamycin plus Metronidazole) as compared with the other programs. This advantage was no doubt due to the use of Metronidazole (used in group 3 only), because of its effectiveness against anaerobic bacteriae.
A prospective, randomized, clinical study was carried out in 188 patients undergoing appendicectomy or colorectal surgery to test the efficacy of prophylactic, parenterally-administered antibiotics in the prevention of infection. The results show the effectiveness of the association gentamicin-metronidazole (9.4% of infections), compared to the control group with no antibiotics (39.1% of infections), X2 = 14.1; P less than 0.001).