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Biomedical subjects

F Czyglik

Publications and source records attributed to F Czyglik.

23 records · Page 2Linked to original sources

Study of sperm morphologic characteristics in a group of 833 fertile men.

For the 13 abnormalities under consideration, the mean percentages were found to be the following: irregular head (15.2), microcephalic (9.8), elongated head (5.9), coiled tail (5.8), bent tail (4.7), thin head (4.6), cytoplasmic remains (3.2), macrocephalic (1.6), short tail (1.1), no tail (0.6), duplicate tail (0.5), duplicate head (0.4), lysis (0.4). In so far as the group studied is representative, the results obtained may be considered as "norms" with the 90th percentiles showing the upper limit of the "normal". The same mean percentages were found by MacLeod and Gold (1951) for the five abnormalities they had identified. The length of abstinence preceding the collection of the ejaculate was found to have no influence on the percentage of abnormal forms.

Age Factors↗

Conception rate according to semen characteristics in a series of 15 364 insemination cycles: results of a multivariate analysis.

The study was undertaken on 1438 ejaculates from 342 donors. The sperm count, volume, prefreeze and postthaw motility were evaluated for each ejaculate and the morphology for the first ejaculate of each donor. The success rate was found to increase steadily with the sperm count, prefreeze and postthaw motility. For the volume and percentage of all abnormal forms, the success rates are stable up to 5,5 ml and 40% respectively and then decrease. Among all the abnormal forms considered, only the microcephalics and irregular heads were found to be linked to the success rate. As most of the studied characteristics are correlated, a multiple stepwise regression was completed in order to determine the proper role of each variable. The most predictive variable is the postthaw motility. The second variable is the percentage of microcephalics. The other variables bring no further information. In particular, at a given postthaw motility, the prefreeze motility and consequently, the loss in motility have no influence on the success rate.

Buffers↗

Abortion rate in A.I.D. and semen characteristics: a study of 1345 pregnancies.

A study undertaken on 1345 pregnancies resulting from artificial insemination with donor showed an 18% risk of abortion. This figure is the same as that admitted for natural reproduction. It does not depend on any of the classically studied semen characteristics and in particular remains invariant whatever the postthaw motility, the factor most strongly linked to conception rate. Two results, well known from the literature, i.e. the increased abortion rate mentioned in natural reproduction when the sperm is of poor quality and the high incidence of repeated abortions when sperm quality is particularly good are discussed. The first of these results cannot be considered as being established in a statistically significant way. The second may result from different sources of bias, some of which are identified. In essence a high frequency of abortions signifies simply a high frequency of pregnancies, it is therefore not surprising that the semen is in this case particularly good.

Abortion, Habitual↗

[Correlation between initial sperm quality and its ability to tolerate cryopreservation].

The aim of this study based on the investigation of 570 semen specimens providing from 251 patients is to determine the correlation existing between initial sperm quality and its ability to bear cryo-preservation. Semen quality was estimated according to the usual parameters : numeration, motility and morphology of spermatozoa. Motility recovery on the one hand, and fertilizing capacity after cryo-preservation on the other hand, allowed an estimation of the sperm ability to bear thawing. Motility recovery seems to depend widely on the initial sperm quality. The persistence of sperm fertilizing capacity partly depends on the motility recovery and consequently partly on the initial quality. However, some semen specimens seem to lose their fertilizing capacity in spite of a good motility after deep-freezing.

Freezing↗