Biomedical subjects

F D Altieri

Publications and source records attributed to F D Altieri.

3 recordsLinked to original sources

PubMed1987

Implantable ventricular assist systems.

A major goal of the Circulatory Support Program of the National Heart, Lung, and Blood Institute (NHLBI) is the development of a tether-free implantable ventricular assist system (VAS) to rehabilitate patients with advanced heart disease. In 1980, the NHLBI initiated a targeted program to develop and integrate implantable electromechanically powered VASs capable of operating for at least 2 years. The objectives of the program are to complete the development of the VAS and perform in vitro and in vivo evaluation studies. This article summarizes the research status of this NHLBI-sponsored program. It defines the VAS system requirements, describes the systems under development, identifies progress achieved to date, and identifies research challenges.

Animals↗

PubMed1986

Mechanical support for the failing heart.

The National Heart, Lung, and Blood Institute (NHLBI) has sponsored considerable research directed toward basic studies on the etiology of heart disease and atherosclerosis. While progress has been very encouraging there are still significant numbers of patients with end-stage heart disease. NHLBI initiated goal-oriented research activities on the artificial heart based upon the recommendation of the National Heart Advisory Council in 1964. The major goal of the Artificial Heart Program was to develop devices which could be effectively used to rehabilitate patients with end-stage heart disease. This paper will describe the evolution and specific program goals of the Artificial Heart Program and provide a description of the left ventricular assist system (LVAS) and total artificial heart (TAH) research efforts. Specific attention will be directed toward defining device requirements, descriptions of the blood pump and energy converter, control system operation and energy transmission methods. A summary of experimental results and current development status will also be provided.

Assisted Circulation↗

PubMed1983

Status of implantable energy systems to actuate and control ventricular assist devices.

A major goal of the Devices and Technology Branch of the National Heart, Lung, and Blood Institute (NHLBI) is the development of a family of devices that can be effectively used in the rehabilitation of patients with advanced heart disease. The development of implantable circulatory assist and total heart replacement devices forms a major portion of this goal. A miniature, implantable energy converter is a key to the development of a tether-free, implantable ventricular assist system. This paper defines the energy system design requirements, identifies key subsystems, briefly reviews NHLBI-sponsored research activities, defines the current research status, and identifies current problem areas and research issues.

Assisted Circulation↗