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Biomedical subjects

F D Hunker

Publications and source records attributed to F D Hunker.

4 recordsLinked to original sources

Tissue plasminogen activator as an alternative to vena cava interruption in recurrent pulmonary thromboembolism.

We have described a woman with pulmonary thromboembolism (PTE) who had acute dyspnea, chest pain, and hypotension during adequate heparin therapy. Pulmonary angiography was consistent with recurrent PTE. The patient was given intravenous TPA and showed significant improvement. Repeat angiography showed resolution of the thrombus in the right main pulmonary artery. The patient did not require vena cava interruption.

Acute Disease

Metabolic and nutritional evaluation of patients supported with mechanical ventilation.

Aggressive nutritional support has been advocated for critically ill patients. Ten patients in a medical ICU supported with mechanical ventilation, 3 on total parenteral nutrition (TPN) and 7 not on TPN, were studied over a 24-h period for oxygen uptake (VO2), carbon dioxide production (VCO2), respiratory exchange ratio (R), and urinary urea nitrogen (UN). Indirect calorimetric formulas were used to calculate the caloric expenditure and this was compared to calories administered. The TPN group had a mean R of 1.23 which was significantly greater than the nonTPN group whose mean R was 0.88 (p < 0.001). The increased VCO2 noted in the TPN group may have been secondary to high carbohydrate intake with fat synthesis and could play a role in patients who are difficult to wean from a ventilator.

Adult

Bacteremia and meningitis following fiberoptic bronchoscopy.

Bacteremia and meningitis due to Streptococcus pneumoniae developed in a 52-year-old man 28 hours after an otherwise uncomplicated fiberoptic bronchoscopy. The patient responded to antimicrobial therapy and supportive care and later underwent pneumonectomy for carcinoma. This report reinforces previous observations that bacteremia may occasionally be associated with the performance of fiberoptic bronchoscopy.

Bronchoscopy