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F D'Abrosca

Publications and source records attributed to F D'Abrosca.

9 recordsLinked to original sources
PubMed2004

[Set up of in vitro methods able to detect the safety of astringent liquids].

AIM: Most of dental operators agree about a gengival retraction impregnated cord in order to obtain an accurate and overwide dental impression. Hemostatic agents allow the formation of the primary coagulum that determines/causes the retraction of gum connective. Sometimes these astringent liquids cause local inflammation reaction as reported in literature. Aim of this work was the evaluation of the cytotoxic and inflammatory action of the most common astringent liquid on human gum primary cells by in vitro tests. METHODS: For this purpose primary cultures of normal human oral keratinocytes were established, following used either as monolayer or as reconstituted model. All dental preparations were dissolved in CEC medium, diluted to the designed concentrations and applied to the cultured cells. The cytotoxicity was determined by using MTT test, able to evaluate the succinate dehydrogenase activity and therefore the cell viability. Control cultures were treated with CED alone, whereas sodium dodecyl sulphate (SDS) was used as a positive control. Furthermore, the inflammatory response, determined by measuring TNF-alpha and IFN-gamma release, was evaluated on a reconstituted multilayer human oral epidermis model. RESULTS: All agents tested showed a dose-dependent increase in the cytotoxicity to normal human gingival keratinocytes over the dose range examined. In particular the results obtained suggest the higher toxicity of the Astringedent X compound. CONCLUSION: The results obtained from the present studies not only provide useful estimates of relative toxicities of these preparations to human oral mucose, but also can be useful as a standard for cytotoxic and inflammatory assessment of newly developed dental preparations to be topically applied to the oral mucosa. It is important to note, however, that the interpolation of these findings to in vivo conditions remains to be done.

Astringents↗
PubMed1995

[Efferent loop obstruction by a phytobezoar after gastrectomy].

The authors present one case of intestinal obstruction due to phytobezoar of the efferent loop, in a previously undergone gastric surgery patient. They report, in the light of bezoar's peculiar location, that is usually it found in the stomach or small bowel.

Aged↗
PubMed1995

[Multiple primary malignant neoplasms].

Multiple primary malignant neoplasms (MPMN) are tumors that arise independently in the same organ or tissues and different organs; they may present simultaneously (synchronous) or at least 6 months later (metachronous). The authors report the case observed: 20 multiple neoplasms in 5 years (5.8% of the tumors). In the light of the international literature they analyze some aspects of the problem, particularly with regard to the classification, etiopathogenesis, neoplasm associations and possible genetic character for some of there.

Adult↗
PubMed1990

[Primary lymphoma of the spermatic cord].

A case of primary malignant lymphoma of the spermatic cord in an eighty-nine-year old man is described. The mass simulated a groin hernia and was misdiagnosed elsewhere. The biopsy stated the presence of high malignant centroblastic lymphoma of the spermatic cord. The patient died few weeks after the diagnosis. The review of the literature permits to stress the rarity of this observation: only seven cases of funicular lymphoma are reported up to now. In all cases there are problems in differential diagnosis with other more frequent inguinocrural pathologies. The tumour of the spermatic cord is therefore an intraoperatory diagnosis. The surgical approach is the treatment of choice but it must be supported by a proper chemotherapy. In any case the prognosis is poor and depends on tumour's staging, clinical behaviour and response to the therapy.

Aged↗
PubMed1990

[Cancer of the male breast with atypical ductal hyperplasia and contralateral gynecomastia].

A case of right mammary invasive ductal carcinoma in young man with atypical ductal hyperplasia and gynecomastia of the second breast is described. The review of the existing literature stress the rarity of this observation. Nevertheless, in all cases of male mammary carcinoma the accurate examination must always include the contralateral breast to search the possible precancerous lesions or etiologic factors.

Adult↗
PubMed1990

[Primary melanoma of the esophagus].

A case of primary malignant melanoma of the esophagus is described. Primary malignant melanoma of the esophagus is rare, reaching only 0.1% of all esophageal tumors. The differential diagnosis is often difficult: the clinical features are similar to those of squamous cell carcinoma and, because of its potentially widespread submucosal growth, the bioptic and/or cytologic examinations are frequently negative. The surgical approach with esophagectomy is actually the treatment of choice. However, the prognosis is poor with a 5-year survival of 4.2%.

Aged↗