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Biomedical subjects

F Daniel

Publications and source records attributed to F Daniel.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

[Localized bullous pemphigoid induced by thermal burn].

BACKGROUND: Induced bullous pemphigoid is known to be triggered by drugs and some physical agents. Six cases of bullous pemphigoid induced by thermal burns have been reported since 1991. CASE REPORT: We observed a bullous eruption around thermal burns of the left leg in a 89 year-old woman. Bullous pemphigoid was diagnosed by histological and immunohistochemical findings with a sub-epidermal blister and linear IgG and C3 deposition at the dermal-epidermal junction. Indirect immunofluorescence was negative. The eruption rapidly resolved with topical steroids. DISCUSSION: We describe a bullous pemphigoid induced by a thermal burn. This case is original because the eruption was localized only around the site of the burn and healed with topical steroids. In the literature, there are 6 other cases reported but only one localized. We discuss the hypothesis of asymptomatic bullous pemphigoid exacerbated by presentation of bullous pemphigoid antigen by thermal burns or self immunization against antigens altered by burns.

Aged↗
PubMedDate not supplied

[Collagen : physiological approach to skin healing,. Its application to the practical treatment of leg ulcers (author's transl)].

Collagen gel has been studied, during a comparative trial, as a topic for cicatrization on a series of twenty patients with severe leg ulcers rebellious to the usual methods of treatment. A complete healing was obtained in 16 cases out of 20, after a period of 8 to 60 days. Collafilm Gel must only be applied to clean, uninfected wounds. It's action seems noticeable by the appearance of network cicatrization, the mechanism and signification of which is being discussed by the authors.

Adult↗
PubMedDate not supplied

[A clinical trial of a new class IV corticosteroid for topical use. Fifty-two case-reports (author's transl)].

A study of the activity of a new corticosteroid for topical use, betamethasone in a propylene glycol vehicle, is reported. The trial was open and included 52 cases. These were mainly severe and chronic cases of atopic dermatitis, psoriasis and intractable prurigos resulting from various causes. The overall results were quite satisfactory, with 80% of good or very good responses. Itching was the feature most frequently improved by this treatment. If atopic dermatitis and psoriasis reacted well the response was particularly satisfactory in lichen planus. Evidence indicating an important effect on adrenal gland function is pointed out. This effect was demonstrated either by decreased serum cortisol levels or by decreased urinary excretion of steroids. This point should be carefully monitored, especially when treating patients with extensive skin disease. Therapy should be discontinued very progressively.

Administration, Topical↗