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Biomedical subjects

F Danieli

Publications and source records attributed to F Danieli.

6 recordsLinked to original sources

Steady state visually evoked potential (SSVEP) topography in a graded working memory task.

The steady state visually evoked potential (SSVEP) elicited by a diffuse 13-Hz visual flicker was recorded from 64 scalp sites in 30 subjects performing a low and high demand version of an object working memory task. During the perceptual component of the task, the SSVEP amplitude was reduced at left and right parieto-occipital sites. During the hold or memory component of the task, the SSVEP amplitude exhibited a load-dependent increase at frontal and occipito-parietal sites, while the SSVEP latency exhibited a load-dependent reduction at central and left frontal sites. We suggest that SSVEP amplitude changes index cortical information processing modes in that perceptual processes are associated with an SSVEP amplitude reduction, while holding information in active short-term or working memory is associated with an SSVEP amplitude increase. We also discuss changes in SSVEP amplitude and latency in terms of changes in the behavior of cortico-cortico and thalamo-cortico loops that utilize cortical layer I. Such cortico-cortico and thalamo-cortical loops are also proposed to constitute a neurophysiological mechanism for holding information in working memory.

Adult↗

[Non-operable malignant neoplasm of the esophagus. A case of necessary palliative oncologic surgery].

The authors examine the clinical evolution of a patient with an oesophageal neoplasm with intraperitoneal liver metastases unnoticed in preoperative phase. Some months after the explorative operation, the patient first underwent a thoracotomy + a cervicostomy with monopolar exclusion of oesophagus because of a mediastinitis caused by a iatrogenic perforation during the attempt to place an oesophageal endoprosthesis; then he underwent a recanalization by presternal subcutaneous oesophago-colonplasty, stimulated by the good result of the surgical operation and by the patient's excellent clinical conditions after the mediastinitis event.

Esophageal Neoplasms↗

[General surgeon and breast reconstruction after mastectomy].

Breast reconstruction is widely used in patients who have undergone mastectomy for breast cancer. The paper underlines that reconstruction is often performed by the general surgeon who has become an expert in this type of plastic surgery. The Authors present their own clinical data, and describe the indications and techniques used, and the results obtained. In conclusion, it is stressed that ideally the same surgeon should be experienced in oncology and plastic surgery.

Adult↗

[Indications for the use of latissimus dorsi myocutaneous flap in breast reconstruction. Personal experience].

The paper illustrates the results of the application of the latissimus dorsi myo-cutaneous flap in breast reconstruction following mastectomy due to cancer in five patients with three different indications. Following a critical evaluation of the indications and results of breast reconstruction using the rectus abdominis myocutaneous flap, the Authors conclude by confirming the validity of indications given and the positive characteristics of the myo-cutaneous flap used.

Adult↗

[Usefulness of long-term follow-up of gastric ulcer: a case load contribution to the natural history of gastric ulcer in relation to treatment with H2-blockaders].

Thorough long-term clinical, endoscopic and biopsy follow-up (from 6 months to greater than 8 years; mean follow-up: 3 years 3 months) of a group of 202 cases of apparently benign gastric ulcer has enabled us to evaluate the natural history of gastric ulcer in relation to medical therapy with H2-blockers and to patient compliance when using such drugs. The results confirm the efficacy of H2-antagonist therapy in gastric ulcer healing and in the prevention of relapse. Thorough follow-up, moreover, made it possible to keep surgical operations for non-neoplastic causes down to very low numbers, only 3 patients (1.5%) being operated on for haemorrhagic emergencies and 12 (6%) for non-response to therapy.

Adult↗

[Usefulness of long-term endoscopic follow-up of gastric ulcer. Study of related epithelial dysplasia].

Over the period from January 1980 to March 1988 the frequency of dysplastic abnormalities associated wits 202 apparently benign gastric ulcers was determined and their course monitored. The relevant data were then evaluated separately for the various subgroups the ulcers were divided into on the basis of their natural history. No correlation was detected between natural history of gastric ulcer, dysplasia and onset of cancer. Though all dysplastic forms (mild, moderate and severe) may regress, all three showed a possibility of progression to EGC, obviously in increasing percentages: mild dysplasia: 2.53%; moderate dysplasia: 4.76%; severe dysplasia: 14.29%. The last of these three values appears to indicate a greater risk of cancer onset than in simple gastric ulcer and thus proves a useful marker for a more thorough monitoring of such patients.

Biopsy↗