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Biomedical subjects

F De Ferrari

Publications and source records attributed to F De Ferrari.

11 recordsLinked to original sources
PubMed2004

Patients' rights versus family rights: the situation in Italy.

The authors, on the basis of Italian legislative and deontological regulation, discuss the problems which are faced in reconciling rights and ethical considerations involving patients and their families. In Italy, with the exception of parents and guardians (for minors and those incapable of consent), there is no family member that Italian law recognises for the purposes of giving consent in the name of another. In all cases, contact with the family must be authorised by the patient in accordance with Law 675/1996 regarding privacy. However, in some situations having the advice of a member of the family can be useful, as it can be of benefit to know the will, tacitly or expressly demonstrated, of the patient. Nonetheless, their opinion cannot be binding on the doctor and he or she is not obliged to request it. Ethically, this usually demands evaluation of almost every case.

Family↗
PubMed2000

A histological procedure to determine dental age.

Sclerosis of dentine has become one of the well established indicators of ageing and age determination. In this study a new technique was reported where a photomicrographic image of a cross section of sclerotic dentine was converted to a grey scale of 256 tones and then reduced to black and white and read by computer using specially developed software. A regression analysis was applied to a sample of 62 teeth (age range 17-84 years) and an age determination within an error limit of 11 years was obtained. Using a Neural Network software however the error was reduced to 8 years.

Adolescent↗
PubMed1999

Age determination by teeth examination: a comparison between different morphologic and quantitative analyses.

Age determination by teeth examination is one of the main means of determining personal identification. Current studies have suggested different techniques for determining the age of a subject by means of the analysis of microscopic and macroscopic structural modifications of the tooth with ageing. The histological approach is useful among the various methodologies utilized for this purpose. It is still unclear as to what is the best technique, as almost all the authors suggest the use of the approach they themselves have tested. In the present study, age determination by means of microscopic techniques has been based on the quantitative analysis of three parameters, all well recognized in specialized literature: 1. dentinal tubules density/sclerosis 2. tooth translucency 3. analysis of the cementum thickness. After a description of the three methodologies (with automatic image processing of the dentinal sclerosis utilizing an appropriate computer program developed by the authors) the results obtained on cases using the three different approaches are presented, and the merits and failings of each technique are identified with the intention of identifying the one offering the least degree of error in age determination.

Journal Article↗
PubMed1996

Italian population data on the loci LDLR, GYPA, HBGG, D7S8 and GC.

Allele and genotype frequencies for the five loci LDLR, GYPA, HBGG, D7S8 and GC were determined for 374 unrelated Italians using a multiplex PCR-amplification and typing commercial kit. The distribution of the genotype frequencies showed no deviations from Hardy-Weinberg expectations. The combined power of discrimination and chance of exclusion for all five loci were 0.999 and 0.702, respectively. A test for homogeneity was performed and no significant differences were observed among the Caucasian population samples.

Alleles↗
PubMed1992

Genetic polymorphism of orosomucoid (ORM1 and ORM2) in Lombardy (Italy).

Orosomucoid subtypes have been analysed in 600 unrelated individuals from the Brescia Area (Lombardy-Italy) by the isoelectric focusing technique and immunoprinting. Five ORM1 phenotypes were observed. The ORM2 pattern was found to be virtually monomorphic, but one variant with an additional single band was found. The estimated allele frequencies were: ORM1*F1 = 0.5992, ORM1*F2 = 0.0150, ORM1*S = 0.3858.

Alleles↗
PubMed1991

Genetic polymorphism of alpha-2-HS glycoprotein in Lombardy (Italy).

Alpha 2HS-subtypes have been analysed in samples from 700 unrelated individuals from the Brescia area (Italy) by the isoelectric focusing technique and immunofixation. The observed allele frequencies were: alpha 2HS*1 = 0.7472; alpha 2HS*2 = 0.2507; alpha 2HS*V = 0.0021.

Blood Proteins↗
PubMedDate not supplied

[The concept of disease and causality relations].

The author recalls the doctrinal and jurisprudential evolution of the concept of disease, with particular reference to the time of onset of the pathological state during the period in which workers are under health surveillance. It is strongly recommended to provide insurance coverage in situations where the worker is transferred for purely preventive purposes and it is equally important to make a strictly accurate assessment of the relationship of causality between exposure to the pathogenic noxious agent and the onset of disease, particularly for penal law purposes.

Disability Evaluation↗