PubMed Health⌕ Search

Biomedical subjects

F Delbos

Publications and source records attributed to F Delbos.

24 records · Page 2Linked to original sources
PubMed1982

[Antibiotic resistance genetic basis of human origin streptococci (author's transl)].

One hundred strains of group A, B, C, D (S faecalis, S. faecium, S. bovis) F, G, S. pneumoniae and viridans streptococci were studied. All these strains were clinical isolates from infective endocarditis and fron upper respiratory, skin, genital and urinary tract infections. These stains were resistant to one or several antibiotics : tetracycline, macrolide and related drugs, chloramphenicol, aminoglycosides (high-level resistance to streptomycin, kanamycin, gentamicin), and penicillin. Conjugative transfer of antibiotic resistance markers (except penicillin) into streptococcal recipients was obtained at a high frequency (10(-1) to 10(-4)) for 12 strains and at a low frequency (10(-5) to 10(-8)) for 29 strains. R plasmids carrying various groups of resistance markers were isolated with different molecular weights. Enzyme restriction analysis showed the existence of different molecular species of streptococcal plasmids. All attempts to detect extrachromosomal DNA in 17 wild-type strains and in the corresponding transconjugants were unsuccessful.

Anti-Bacterial Agents↗
PubMed1979

High-level, plasmid-borne resistance to gentamicin in Streptococcus faecalis subsp. zymogenes.

Each of three isolates of Streptococcus faecalis subsp. zymogenes harbored three R plasmids and a hemolysin-bacteriocin plasmid. The plasmids carried by one of these strains were physically characterized after their conjugative transfer. In each strain one of the plasmids carried genetic markers for resistance to gentamicin, kanamycin, sisomicin, netilmicin, and tobramycin.

Anti-Bacterial Agents↗
PubMedDate not supplied

[Viridans streptococci in human infections: identification and susceptibility to antibiotics].

A method for the speciation of viridans streptococci (devoided of group antigens) is described. The major identification criteria are based on the reaction of a series of biochemical tests such as acid production in lactose, inuline, raffinose, mannitol and sorbitol, hydrolysis of arginine, esculin and Na hippurate, and production of polysaccharides in 5% sucrose media. A total of 460 strains were isolated from human specimens and identified as follows: 118 Streptococcus mitis, 102 S. sanguis II, 75 S. Sanguis I, 87 S. milleri (Streptococcus MG-intermedius), 28 S. mutans, 25 S. salivarius, 14 S. morbillorium, 2 S. uberis and 9 unspeciated. Susceptibility to antibiotics was studied for 318 strains: 63% of them were susceptible to all drugs tested; 37% of the strains were resistant to one or several antibiotics as follows: 34% to tetracycline, 8.5% to macrolides and related drugs, 5.3% to streptomycin and/or kanamycin (MIC greater than 2,000 micrograms/ml), 5% to penicillin (MIC = 1-4 micrograms/ml) and 4% to chloramphenicol.

Anti-Bacterial Agents↗
PubMedDate not supplied

[Group D streptococci in human infections: identification and sensitivity to antibiotics (author's transl)].

A method for the speciation of group D streptococci is described. A major criterion for identification is the reaction of antigenic extracts against streptococcal group D antisera. In addition, a series of biochemical tests is used: bile-esculine, resistance to 6.5% sodium chloride and potassium tellurite, acid production in mannitol, sorbitol and raffinose, hydrolysis of starch and arginine, and production of dextran. A total of 184 strains was isolated from human material and identified as follows: 104 S. faecalis, 18 S. faecium, 8 S. durans, 2 S. avium, 51 s. bovis and 1 unspeciated. The sensitivity to antibiotics was studied for 141 strains: 34% were sensitive, 23% were singly resistant to tetracycline and 43% were multiply resistant (tetracycline, macrolides and related drugs, high-level resistance to aminoglycosides and to chloramphenicol).

Anti-Bacterial Agents↗
PubMedDate not supplied

[Characteristics of "Streptococcus mutans" from endocarditis and susceptibility to antimicrobial agents (author's transl)].

Strains of Streptococcus mutans were isolated from blood cultures of ten patients with endocarditis. Nine of these patients had a typical clinical picture of subacute bacterial endocarditis, with fever, weakness, heart murmur and multiple positive blood cultures. All the patients had previous valvular heart diseases; only in three cases the initiating event involved some type of dental manipulations which where supposed as the source of infection. The major criteria for recognizing S. mutans were colony morphology on blood agar, characteristic extracellular polysaccharide production in 5% sucrose broth, acid formation in mannitol and sorbitol broth, and the failure of antigenic extracts of S. mutans to react with streptococcal group antisera. The susceptibility to antimicrobial agents was tested by the diffusimetric method with susceptibility disks. All the strains were susceptible to penicillin G, erythromycin, pristinamycin, lincomycin and tetracycline, and resistant to streptomycin and gentamicine.

Endocarditis, Subacute Bacterial↗