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Biomedical subjects

F Delrieu

Publications and source records attributed to F Delrieu.

At least 37 records · Page 2Linked to original sources
PubMed1983

[National survey on reactive arthritis by the French Society of Rheumatology].

In 1982, 3370 cases of inflammatory rheumatism were declared. The geographical analysis of the distribution of these cases (departmental and regional) suggests that their distribution is not homogeneous throughout the country, with a predominance of psoriatic arthritis in the Midi and the Pyrenees and a predominance of rheumatic pelvispondylitis in Aquitaine. Based on the number of cases declared, we can calculate the distribution of each type of inflammatory rheumatism by age and by sex and the incidence per million inhabitants in each age group. These figures are only indicative, as the data from some departments was incomplete. The calculation of a "criterion of frequency" attempts to equalize this bias. Reactive arthritis (352 cases) represents 10.4 p. cent of all cases of inflammatory rheumatism. This large series collected over one year confirms the clinical data already established. The responsible organisms, by order of frequency, were: Chlamydia trachomatis, Yersinia enterocolitica, Shigella, Y. pseudotuberculosis and Ureaplasma urealyticum. 50 p. cent of these cases of arthritis were classified as reactive on the basis of clinical findings and history and the bacteria was not isolated. The HLA-B27 antigen is present in 68 p. cent of the 302 cases in which it was tested.

Adolescent↗
PubMed1982

[Pulmonary lesions in dermatomyositis. A retrospective study of 4 cases].

During a retrospective study of the records of 9 patients with dermatomyositis, pulmonary lesions were noted in 4 cases. Dermatomyositis had been diagnosed on clinical, biochemical, electrical and histopathological criteria. Patients with other connective tissue disease associated with dermatomyositis were excluded. In one case the pulmonary lesions preceded the clinical symptoms of dermatomyositis. Two patients had interstitial pneumonia and 2 presented with reticulonodular images suggestive of diffuse interstitial fibrosis. The outcome after corticosteroid and/or immunosuppressive therapy was favourable in 3 cases. It would appear from this study that clinical and radiological signs of pulmonary lesions and respiratory insufficiency are abnormally frequent in dermatomyositis and that the prognosis in such cases is perhaps brighter than is usually believed.

Adult↗
PubMed1981

[Infectious sacroiliitis. Multicenter study of 214 cases].

Out of 214 cases of infective sacro-ileitis observed on Rheumatology Units, 65% were due to common bacteria, 25% were tuberculous and 10% due to brucellosis. Post-partum infections were early, severe and often due to streptococci. Sacrocoxalgia was accompanied in 50% of cases by another focus of active tuberculosis. Two clinical presentations are possible, either that of acute sacro-ileitis with a sudden onset, severe pain, frank infection and major impotence which is common in infections due to current bacteria; or the presentation may be that of subacute sacro-ileitis with progressive onset with little or no fever, pain and moderate impotence which may be due to any bacteria. Identification of the responsible organism depends on blood culture, bacterial sampling at the point of entry of the infection but, above all, direct swab or preferably needle biopsy. Bone scan may demonstrate early hyperfixation in the absence of any radiological signs. Prolonged antibiotic treatment is sufficient in most cases.

Adolescent↗
PubMed1976

Controlled trial of D-penicillamine in rheumatoid arthritis. Dose effect and the role of zinc.

The findings are reported of a controlled clinical trial comparing in 66 rheumatoid arthritis patients 0 g (placebo), and 0.50 g a day and 1 g a day of penicillamine. Each of these groups has been subdivided into two, one part receiving 5 mg a day of zinc metal supplement, the other a placebo. The trial was planned to be double-blind, and for each patient to take part for 4 months. The results prove the effectiveness of penicillamine in rheumatoid arthritis. 0.50 g a day has the same effect as 1 g a day but gives less side effects. Zinc supplement inhibits the clinical effects of penicillamine but does not prevent the side effects.

Arthritis, Rheumatoid↗
PubMed1975

Pyogenic infection of the sacro-iliac joint. Report of thirteen cases.

Thirteen cases of infectious sacro-iliitis caused by pyogenic organisms are reported and compared with thirty-four cases in the literature. Staphylococcus was the commonest infecting organism (six cases). Two clinical patterns were noted, acute (nine cases) and subacute (four cases). Treatment was by antibiotics and bed rest in all patients. Surgery was indicated for diagnosis in three patients and for abscess in three patients. All of our patients had very good functional recovery.

Adolescent↗