[Organic ammonium salts. I. Synthesis of 1,1-dialkylpiperidinium bromides and antimicrobial activity].
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Bacteria↗
Biomedical subjects
F Devínsky
Publications and source records attributed to F Devínsky.
Antimicrobial activity of quaternary ammonium salts of some saturated heterocycloalkyl amines [1].
Antimicrobial activity of N-alkyl-N-dodecylpiperidinium bromides and N-ethyl-N-dodecylheterocycloalkyl ammonium bromides (pyrrolidine, morpholine, perhydroazepine) determined on grampositive and gramnegative bacteria, yeasts and moulds, presented as minimum inhibition concentration (MIC). Comparison of the effect of change of structure: lengthening of alkyl chain, change of heterocyclic ring. Change in the length of alkyl chain markedly affects the antimicrobial activity, change of heterocyclic ring has no substantial effect. The most active compounds were N-heptyl-and N-hexyl-N-dodecylpiperidinium bromides.
Anti-Bacterial Agents↗
Antimicrobial activity of N,N'-bis(decylmethyl)-alpha,omega-alkanediamine dioxides [1].
Antimicrobial activity of N,N'-bis(decylmethyl)-alpha,omega-alkanediamine dioxides determined on Staphylococcus aureus, Escherichia coli, and Candida albicans is presented as minimal inhibitory concentration (MIC). The effect of the length of linking alkylene chain on this activity has been followed.
Anti-Bacterial Agents↗