Late perforation of a mediastinal oesophagocoloplasty.
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Adult↗
Biomedical subjects
F Doncel
Publications and source records attributed to F Doncel.
Non-surgical closure of a benign oesophagobronchial fistula.
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Bronchial Fistula↗
VP16-213 and cyclophosphamide in advanced breast cancer. A phase II study.
Twenty-seven patients with histologically proved advanced breast cancer were given VP 16-213 and cyclophosphamide. Twenty-one had shown resistance to other chemotherapy schedules and six had experienced relapse during adjuvant chemotherapy. There were four complete responses (15%) and seven partial responses (26%). Median survival was 61 weeks and median duration of response was 31.4 weeks. All patients experienced gastrointestinal toxicity and 22 patients (81%) showed bone marrow toxicity. This regimen is effective in advanced breast cancer resistant to other chemotherapy regimens.
Adult↗
Retrorectal cyst-hamartomas. Report of two cases with adenocarcinoma developing in one.
The clinical and pathological features of two cases of retrorectal cyst-hamartoma are presented. Both lesions were characterized by the presence of cysts lined by mucus-producing, ciliated and transitional epithelium. The anatomical and histological findings in our cases of retrorectal cyst-hamartoma are in favor of an embryologic origin from remnants of the postanal gut. The differential diagnosis includes teratomas, dermoid cysts, duplication cysts of the rectum, anal gland cysts, and anal gland carcinomas. To avoid complications, particularly malignant transformation, early complete excision is recommended.
Adenocarcinoma↗