PubMed Health⌕ Search

Biomedical subjects

F E Dische

Publications and source records attributed to F E Dische.

25 records · Page 2Linked to original sources
PubMed1976

Pneumococcal antigen in pneumonia. A post-mortem study with the histological and bacteriological findings.

Pneumococcal capsular antigens can be detected in lung tissue by counter-current immunoelectrophoresis even when, following antibiotics, post-mortem bacterilogy suggests that Escherichia coli has replaced pneumococci. The results suggest that antipneumococcal therapy would benefit at least 55% of patients critically ill with lung infection and that the potentially toxic drugs directed at coliform bacteria may be unnecessary.

Aged↗
PubMed1976

Immunopathology of penicillamine-induced glomerular disease.

Four patients with rheumatoid arthritis developed heavy proteinuria after five to 12 months of treatment with D-penicillamine. Light microscopy of renal biopsy samples showed minimal glomerular capillary wall thickening and mesangial matrix increase, or no departure from normal. Electron microscopy, however, revealed subepithelial electron-dense deposits, fusion of epithelial cell foot processes, and evidence of mesangial cell hyperactivity. Immunofluorescence microscopy demonstrated granular capillary wall deposits of IgG and C3. The findings were similar to those in early membranous glomerulonephritis, differences being observed however in the results of staining for the early-acting complement components C1q and C4. It is tentatively concluded that complement was activated by the classical pathway.

Arthritis, Rheumatoid↗
PubMed1968

Argentaffin and non-argentaffin carcinoid tumorurs of the appendix.

Tumours of the vermiform appendix were studied. The majority proved to be carcinoid tumours of the usual argentaffin-positive type but a substantial minority, generally tumours of minute size, were found to have a somewhat different histological pattern and were argentaffinnegative. Some contained argyrophil granules. The non-argentaffin tumours are considered to form a subgroup of carcinoid tumours.

Adult↗