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Biomedical subjects

F E Klee

Publications and source records attributed to F E Klee.

4 recordsLinked to original sources

Severe abdominal pain and thrombocytopenia--typical symptoms of occult jejunal diverticulum perforation?

Complicated small-bowel diverticula cause abdominal pain, gastrointestinal hemorrhage, small-bowel obstruction, and peritonitis. The present patient, had an occult perforation of a small-bowel diverticulum. There were diverticula throughout the whole small bowel. Preoperatively thrombocytopenia (98,000 thrombocytes/cc), was noted. Without any special treatment, i.e., transfusion, the thrombocyte level increased after surgical treatment to normal levels. Although the incidence of small-bowel diverticula appears to be low (0.1%-2.3%) complications may become life-threatening. The level of thrombocytopenia may reflect the extent of inflammation.

Abdominal Pain↗

[Splenic cyst--a classical "incidental finding"].

Splenic cysts cannot be summarized in one entity but open a wide field of aetiopathogenetic factors. The most common types of splenic cysts in central Europe are of epithelial or traumatic origin. Since ultrasound is widely used, the incidence of splenic cysts increased to about 1%. Rarely, splenic cysts give specific symptoms. Giant cysts cause unspecific abdominal pain, sometimes even organ displacement, possibly leading to a decreased function of related organs. In case of rupture, splenic cysts may become life-threatening. We present a patient suffering a giant splenic cyst and give an overview of diagnostic and therapeutic aspects of splenic cysts.

Adolescent↗

The reliability of highly elevated CA 19-9 levels.

CA 19-9 is used as a tumour marker of the upper gastrointestinal tract. However, extremely elevated CA 19-9 levels are found also in patients with benign diseases. Cholestasis was present in 97.1% of patients with high elevated CA 19-9, independent of their primary disease. 50% of patients with non-malignant diseases and increased CA 19-9 levels showed liver cirrhosis, cholecystitis, pancreatitis and/or hepatitis. In 8.8% no explanation was found for the extremely high CA 19-9 level. The results provide evidence of different factors influencing the CA 19-9 level.

Antigens, Tumor-Associated, Carbohydrate↗