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Biomedical subjects

F E Lucente

Publications and source records attributed to F E Lucente.

At least 37 records · Page 2Linked to original sources

Safety awareness for the otolaryngologist caring for the HIV-positive patient.

The alarming increase in human immunodeficiency virus (HIV) infection, expected to reach 40 million cases worldwide by the year 2000, has enormous impact on the otolaryngologist, since up to 70% of HIV-positive patients present with head and neck symptoms. Parenteral and nonparenteral acquisition of HIV has been documented with seroconversion from needle sticks estimated at 1 for every 200 exposures. The rate of compliance with universal precautions is found to be reported as low as 16%. In 1993, over 1400 patients with HIV were admitted to Kings County Hospital Center. There were 165 reported cases of sharp injuries of which 4 were scalpel related and 17 were suture needle related. We surveyed HIV safety experiences at five hospitals emphasizing operating room procedures, including instrument handling, gloving, elimination of excess equipment and personnel, utilization of nonsharp instruments, and team discipline. Preventive measures are recommended to help minimize inadvertent sharp injuries.

HIV Infections↗

Laryngeal tuberculosis in HIV-infected patients: a difficult diagnosis.

Unrecognized laryngeal tuberculosis (TB) poses a significant hazard to otolaryngologists. However, the changing manifestations of TB in patients with human immunodeficiency virus (HIV) infection can make its diagnosis difficult. In our population of 146 patients with TB involving the head and neck, HIV infection was present in 70 cases (48%). The prevalence of laryngeal TB in this population was 5.5% (8 patients). Concomitant HIV infection was present in 2 (25%) of 8 patients with laryngeal TB. A delay in the diagnosis of laryngeal TB occurred in 100% of patients with HIV infection, compared with 17% of non-HIV-infected patients (P = .055). The cause of the delayed diagnosis was multifactorial, mainly the presence of multiple confounding variables and the carcinoma-like appearance of the laryngeal TB lesions in HIV-infected patients. To reduce risk for transmission of TB to health care providers, a high level of suspicion must be present for all patients with laryngeal lesions, especially those with HIV infection.

Adult↗

Acute postobstructive pulmonary edema.

Acute postobstructive pulmonary edema may occur after airway obstruction. A decrease in intrathoracic and intraalveolar pressures causes an increased blood flow into the pulmonary vasculature and favors the development of pulmonary edema. Two mechanisms for the development of acute postobstructive pulmonary edema are proposed: type 1 follows acute airway obstruction, and type 2 follows relief of chronic airway obstruction.

Acute Disease↗

Retropharyngeal abscess: clinical review.

Retropharyngeal abscess, once a relatively common entity in children, is uncommon today. From 1981 to 1991, we treated 20 cases. Abscesses secondary to upper respiratory infection in children were seen only in three (15%) cases. Trauma and foreign bodies were the most common etiologic factors in the adult subgroup. Streptococcus viridans and Klebsiella pneumoniae were the most common pathogens. The use of contrast-enhanced computed tomography has had a significant impact on the diagnostic work-up. The choice of initial antibiotic therapy is discussed. There were no deaths in this series.

Adolescent↗

Changing trends in deep neck abscess. A retrospective study of 110 patients.

We have conducted a retrospective study of 110 patients with the diagnosis of deep neck abscess who had been seen between 1981 and 1990. Etiologic factors, common pathogens, and antimicrobial therapy were reviewed with reference to diagnostic methods of choice and management principles. The findings were compared with the literature. We have identified trends of change in the following aspects of deep neck abscess: cause, presentation, diagnostic methods, and bacteriology. Management principles of airway protection, intravenous antibiotics, and drainage have not changed.

Abscess↗

Lymphatic drainage system after left radical neck dissection.

The thoracic duct is the main lymphatic vessel that drains most of the body's lymph and all of the intestinal chyle into the venous system. The thoracic duct may be ligated during left radical neck dissection (RND) without any significant sequelae. The lymphatic system must, therefore, have collateral channels. The present study shows an increased incidence of pleural effusion after left RND when compared to right RND. We suggest that this represents the inability of the collateral system to immediately accommodate the increased volume of chyle.

Carcinoma, Squamous Cell↗

Kaposi's sarcoma of the head and neck in patients with acquired immunodeficiency syndrome.

Kaposi's sarcoma is the most common neoplastic process in patients infected with the human immunodeficiency virus. Moreover, the occurrence of Kaposi's sarcoma in human immunodeficiency virus-infected patients advances their classification to having the acquired immunodeficiency syndrome. We reviewed the medical records of 48 patients with human immunodeficiency virus infection who had Kaposi's sarcoma documented on their initial visit to the hospital. The onset of Kaposi's sarcoma occurred independent of the Centers for Disease Control and Prevention classification of human immunodeficiency virus infection (modified to exclude Kaposi's sarcoma). This neoplasm developed more frequently in patients who acquired human immunodeficiency virus infection by sexual contact (75% of cases), but manifestations were not significantly different in any of the risk populations for human immunodeficiency virus infection. Kaposi's sarcoma lesions were unpredictable and either showed progression, remained static, or occasionally, regressed spontaneously. Moreover, the lesions were usually multifocal at presentation, with the head and neck (62.5% of cases) as the primary site of involvement. In this region cutaneous lesions predominated (66.7%), followed by mucosal (56.7%) and deep structure (13.3%) involvement. The majority of patients with acquired immunodeficiency syndrome Kaposi's sarcoma involving head and neck structures were asymptomatic (80% of cases). Mucosal lesions were associated with symptoms in 29.3% of cases, whereas cutaneous lesions had symptoms in 5% of cases.

Acquired Immunodeficiency Syndrome↗

Ear lobe keloids, surgical excision followed by radiation therapy: a 10-year experience.

This retrospective study was conducted to analyze the recurrence of ear lobe keloids in 36 patients after surgical excision followed by radiation therapy. In all the cases keloids were excised and the surgical wound closed primarily. Following surgery, patients underwent 1800 cGy of radiation therapy in three equally divided doses over five to seven days. Most of our patients were young black females who developed keloids secondary to ear lobe piercing. Of the 36 patients followed for a mean period of 5.6 years, we noted only one (2.8%) recurrence. All the patients were followed for a minimum of two years. No serious complications were observed in our series. However, one patient developed radiation dermatitis followed by patchy hypopigmentation. We conclude that surgical excision followed by radiation therapy is a safe and effective method to control keloid recurrence in the ear lobe region.

Adult↗

The treatment of rhinophyma. 'Cold' vs laser techniques.

OBJECTIVE: To compare laser surgery and sharp blade excision of rhinophyma. DESIGN: Retrospective study of 23 patients treated surgically for rhinophyma. SETTING: Four academic tertiary referral medical centers. PARTICIPANTS: All 23 patients had moderate or major rhinophyma. INTERVENTION: Sixteen patients had laser surgery. Seven patients had sharp blade excision. OUTCOME MEASURES: Length of the procedure, preservation of normal tissue, the need for skin grafting, intraoperative pain and discomfort, intraoperative bleeding, postoperative pain and discomfort, postoperative bleeding, complications, and end results (all listed in the literature as advantages of laser surgery). RESULTS: No difference in length of surgery, preservation of normal tissue, complications, postoperative pain, and end results. No need for skin grafting in both procedures. Less intraoperative and postoperative bleeding, easier and smoother procedure, and more comfortable postoperative care with laser surgery. CONCLUSIONS: Our results do not agree with most of the list of advantages attributed to laser rhinophyma surgery in the literature.

Aged↗

Resection of tracheal stenosis with end-to-end anastomosis.

We present our experience with circumferential tracheal resection with end-to-end anastomosis. Between 1985 and 1992 we performed this procedure on 19 patients with tracheal stenosis. The cause of the stenosis was related to intubation and/or tracheotomy in 78.9% of the patients. Two to 8 tracheal rings were resected and a tension-free anastomosis was achieved with mobilization techniques that were limited to suprahyoid release, peritracheal dissection, and chin-to-chest suture. Infrahyoid release and intrathoracic perihilar mobilization techniques were not used. The anastomosis success rate was 94.7%.

Adolescent↗

Fungal infections of the external ear.

Fungal infections of the external auditory canal can pose a great clinical challenge both in diagnosis and in therapy. Most infections present in patients who have undergone previous medical treatment of the external canal, which has changed the pH and normal canal flora, or in those who have diminished capacity for resisting infections. Diagnosis is made by clinical inspection and selective cultures. Therapy consists of complete cleaning followed by use of topical antimycotic agents. Systemic therapy is rarely required.

Humans↗

Impact of the acquired immunodeficiency syndrome epidemic on the practice of laryngology.

In only 10 years, the acquired immunodeficiency syndrome epidemic has already had an enormous impact on many aspects of the practice of medicine. The practice of laryngology typifies the changes that have occurred. Heightened clinical vigilance has been required as the laryngologist encounters new and unusual manifestations of the disease and must take more extensive histories regarding social, behavioral, and sexual practices than were previously necessary. The performance of physical examinations and surgical procedures has also changed as a result of experience with the lethal human immunodeficiency virus. Numerous legal, ethical, and social issues have also been raised by the epidemic and have had a major influence on how medicine is practiced and regulated. In this paper we review the laryngeal and pharyngeal manifestations of acquired immunodeficiency syndrome and discuss illustrative patient examples that demonstrate the impact of the disease. We also consider the diverse groups of issues that attend this epidemic and that continue to modify practice patterns.

Acquired Immunodeficiency Syndrome↗

Keloid.

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Humans↗