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Biomedical subjects

F E Müller

Publications and source records attributed to F E Müller.

At least 37 records · Page 2Linked to original sources

[The effect of burns on the complement system].

Serum levels of total complement CH 50 and the complement components C1, C1 inactivator, C2, C4, C3c, and C3 activator were measured in 20 patients with burn injuries. The findings were assessed for any possible correlations between the results of serological investigations, severity of burns and clinical aspects of the patients.

Adolescent↗

[In-vitro efficacy of topical antibiotics on bacteria from burns].

The influence of topical antimicrobial agents on bacterial growth was determined with an agar diffusion technique. 349 isolates were tested with mafenide acetate and silver sulfadiazine, 226 isolates were tested with povidone iodine. None of these agents was likewise effective against all organisms of the same bacterial strain. The inhibition of growth by mafenide acetate and silver sulfadiazine demonstrated dose-response. 26 to 40% of the tested grampositive cocci were inhibited by mafenide acetate, whereas the growth of about 26 to 90% of gramnegative rods was effected by silver sulfadiazine, with the exception of proteus species (9%). Both agents influenced the growth of pseudomonas (40 to 65%). The results obtained with povidone iodine led to the consideration that the agar diffusion method might not be suitable for testing this drug.

Anti-Bacterial Agents↗

[Debridement of burns with proteolytic enzymes from Bacillus subtilis].

50 patients with burns received an enzymatic debridement with bacillus subtilis (Protease-ointment = Travase. Symmetrical control sites were treated without Protease-ointment simultaneously. With the help of Protease-ointment early eschar removal was achieved in deep dermal burns. In full thickness burns the success of the treatment was dependent on the depths of the tissue damage and the early application of Protease-ointment, which allowed the removal of the dermal elements of the eschar whereas fat remained unaffected. In our experience Protease-ointment can be considered a valuable method of eschar removal in addition to surgical measures.

Bacillus subtilis↗

[Cancellous bone grafting for fingers and metacarpus].

Bone grafting using cancellous bone is a reliable method treating fresh and old fractures. In the period 1974-1977 the Department of Plastic Surgery of the University Hospital "Bergmannsheil Bochum" treated 39 cases of finger- and metacarpal-bone injuries and bone diseases successfully by cancellous bone grafting. Indications, technique and results of our methods are described.

Adult↗

[Experience with deep-frozen fresh pig skin in the treatment of 100 burn injury patients].

Our report is based on the treatment of 100 extensive burns with the employment of fresh frozen porcine skin used as biological dressings. Our experience shows that fresh frozen porcine skin equals in most respects non-typed homografts. Its utilization is economical and it is also recommended in cases where the number of human donors is limited.

Biological Dressings↗

[Problems in intensive care for burns (author's transl)].

Severe burns are followed by a shock period of more than 48 h. Insufficient fluid replacement may lead to serious organic damage. Protein losses are high. Cardio-respiratory complications are frequent. Infection and sepsis are still frequent causes of death. Skin damage requires extensive operations for debridement and skin replacement, and blood losses must be replaced simultaneously.

Adolescent↗