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F Etcharry-Bouyx

Publications and source records attributed to F Etcharry-Bouyx.

13 recordsLinked to original sources
PubMed2006

What about theory of mind after severe brain injury?

BACKGROUND: Behavioural changes are often reported after a severe traumatic brain injury (TBI). These changes are usually a greater burden for relatives than physical or cognitive impairments. This study investigated social cognition in TBI patients using two theory of mind (TOM) tasks. METHOD: The performances of 17 patients with severe TBI and 17 matched controls were compared on two tasks designed to investigate understanding of other people's mental states: The 'Reading the Mind in the Eyes' test (RME) and the 'Character Intention Task' (CIT). TBI patients and controls were also given several executive function tasks. RESULTS: Compared to healthy controls, patients were impaired in most executive tests and in both TOM tasks. No relationship was found between TOM and executive measures. This is consistent with Rowe's position, who suggested an independence between executive functioning and social cognition. These data suggest that TBI patients may have specific social intelligence disturbances. CONCLUSION: Future work should employ additional tests of TOM and behavioural ratings and recruit more patients in order to complete analysis.

Adolescent↗
PubMed2003

Two clinicopathological cases of a dominantly inherited, adult onset orthochromatic leucodystrophy.

Leucodystrophies of orthochromatic type are a heterogeneous group that occur mainly in childhood and have no known enzyme deficiency. We report here the clinicopathological features of a new family of orthochromatic leucodystrophy with three main characteristics: a probably autosomal dominant inheritance; two phenotypes based on age of onset; and very few abnormalities of white matter on MRI findings in one case. The first patient, aged 58 years, had frontal dementia and epilepsy; the second, aged 38 years, had motor signs and dementia, but no epilepsy. The histopathological features of our two cases were leucodystrophy of orthochromatic subtype. However, the radiological features (MRI and mostly FLAIR sequences) of the first case did not suggest leucodystrophy.

Adult↗
PubMed2003

[Gestual apraxia].

Explore the source record for details and available documents.

Apraxia, Ideomotor↗
PubMed2001

A case study of selective impairment of the central executive component of working memory after a focal frontal lobe damage.

RC is a 36-year-old man who sustained a closed head injury with bilateral frontal lobe hypometabolism in 1978. In 1994, after a lobectomy of a large part of the left frontal lobe, he presented no behavioral disruption and normal performances on most of intelligence, long-term memory, and executive tests. However, he showed deficits in tasks that implicate short-term storage (i.e., span tasks). These deficits in working memory were explored with regard to Baddeley's model using computerized tasks. On these tasks RC showed normal functioning of the articulatory loops and dysfunction of the central executive component in dual tasks. These results confirm those reported in another single case study by Van Der Linden, Coyette, and Seron (1992) and indicate that dual-task performance may assess one separable feature of executive functions.

Adult↗
PubMed2001

Influence of centrality and distinctiveness of actions on script sorting and ordering in patients with frontal lobe lesions.

In order to further investigate script knowledge in patients with frontal lobe lesions (FP), 30 participants with frontal brain damage, 14 controls with posterior brain damage (PC) and 30 normal controls (NC) were asked to sort script actions with various degrees of centrality and distinctiveness according to the script to which they belonged and their order of execution. Actions were given in 3 conditions: scripts with headers (SH), scripts without headers (SwH) and scripts with distractor header (SDH). Results confirmed the dual dissociation we observed in a previous study (Allain, Le Gall, Etcharry-Bouyx, Aubin, & Emile, 1999). Twelve FP made numerous errors in sequencing actions regardless of the conditions, but rejected the irrelevant title. Fourteen FP made few sequencing errors but used the irrelevant title. The last 4 FP performed as well as the PC and NC in every condition. Sorting errors made by the FP mainly concerned actions with low levels of centrality and distinctiveness. These data are consistent with the view that frontal lobe lesions selectively impair the syntactic component of script representation without affecting its semantic component.

Adult↗
PubMed2000

[Design of a force sensor to evaluate the grasping movement].

Grasping phenomena are abnormal motor behaviours described after cerebral lesions. They are defined as a stereotyped response, consisting of a progressive forced closure of the patient's hand on the examiner's fingers, when they are slowly moved exerting a strong pressure across the palm in an upward direction. Several types are described. The aim of the study was to develop a force sensor to evaluate the force of grasping in accordance with the force of dragging. The characteristics of this force sensor are presented and the clinical application in two selected patients demonstrated.

Aged↗
PubMed2000

[Incidence of grasping and its relationship to cerebral lesions].

Grasping is associated with frontal lobe pathology. Nevertheless, there is lack of precise anatomical correlations and very few studies are published. The aim of the study was to determine the incidence of the grasping and its relationship to cerebral lesions. We studied 236 patients admitted to the Neurology Department (108 women and 128 men; mean age 65.3), and tested with a standardized procedure (De Renzi and Barbieri, 1992). A score of grasping was determined for each patient. The locations of the cerebral lesions were assessed by two neurologists using the method of Damasio and Damasio (1989). Grasping was found in 38 patients (16.1p.100) with dementia or cerebral damage. In all cases, the lesion affected the frontal lobe. The patients with grasping showed a significant higher number of lesioned areas particularly for the frontal and the parietal regions. The score of right grasping was significantly higher with a lesion in the right paraventricular frontal and in the left parietal paraventricular areas. The score of left grasping was significantly higher with a lesion in the left frontal paraventricular area. These results are discussed in relationship with motor control.

Age Factors↗
PubMed1999

Mental representation of knowledge following frontal-lobe lesion: dissociations on tasks using scripts.

Twenty-three frontal-brain-damaged subjects, 10 posterior-brain-damaged subjects and 10 normal controls were compared on script tasks. They were first asked to re-establish the sequential and hierarchical structure of 2 script actions, and then, they were asked to order 2 new scripts which contained aberrant items. Impairments in script information processing were observed only in frontal patients. Of the 23 frontal patient tested 8 made errors in ordering actions, in choosing scenes and in making estimates of action importance in the first task, and they rejected the aberrant elements in the second task. Eleven frontal subjects performed as well as the control subjects in the first task, but used the irrelevant items. The last 4 frontal patients performed as well as the control subjects in both tasks. These results support a possible fractionation of the frontal lobe syndrome.

Adult↗
PubMed1995

[Fahr's disease and mitochondrial myopathy].

The case of a 41 years old man presenting with mitochondrial myopathy associated with calcification of the basal ganglia (Fahr's disease) neurosensorial and endocrine-deficits is reported. These different symptoms could share a common physiopathological process.

Adult↗
PubMedDate not supplied

Acute delirium, delusion, and depression during IFN-beta-1a therapy for multiple sclerosis: a case report.

Adverse effects of interferon (IFN) treatment are common, and efforts to minimize these reactions are of considerable importance. IFN-beta-1a is an established therapy for patients with relapsing-remitting multiple sclerosis (MS). Its psychiatric side effects are debated and not yet fully established. The authors report here the case of a patient on IFN-beta-1a therapy for MS who developed acute delirium, delusion, and depression that ceased with treatment discontinuation. Although he had a history of recurrent major depressive disorder, his prior psychiatric illness had followed a course that was clinically independent of other signs of MS. This observation points out psychiatric vulnerability of patients taking IFN-beta-1a therapy for MS and suggests that IFN-beta-1a may induce or exacerbate preexisting psychotic symptoms.

Adjuvants, Immunologic↗
PubMedDate not supplied

[Cognition disorders and parkinsonian syndrome: diffuse Lewy body disease?].

A 68 year old man developed progressive cognitive impairment with an akinetic-rigid syndrome which was atypically responsive to levodopa. The patient died after 18 months and the postmortem examination showed typical Lewy bodies in the substantia nigra and pale bodies in the cortex which were unlabelled by ubiquitin antibodies. This case is particular by the neuropathological examination (no immunoreactivity to antibodies against ubiquitin) and by the abnormal response to treatment (dystonia). These two aspects are discussed.

Aged↗