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Biomedical subjects

F F Bartone

Publications and source records attributed to F F Bartone.

45 records · Page 3Linked to original sources

Reaction of the urinary tract to polypropylene sutures.

Cystotomies were performed on 99 mature guinea pigs and closed with polypropylene sutures. The bladders were removed at intervals from day 4 through day 144 postoperatively. They were studied with both light and electron microscopy. A localized mild, acute, inflammatory reaction was noted transitorily; it subsided between the 7th and 14th day. Three calculi were formed, a result which compares favorably with studies of other sutures. Results indicate that the suture may have a place in urologic surgery, but further studies are necessary before clinical use.

Animals↗

Smooth muscle regeneration in swine ureters: a light and electron microscopic study.

Intubated ureterotomies were performed on 16 juvenile pigs. The animals were killed at intervals of from 2 to 91 days after operation and tissue sections examined with light and electron microscopes. Ureteral wall replacement occurred within the 3 months after operation and included all tissue layers. Epithelialization of the wound surfaces occurred in the 1st week and was accompanied by a connective proliferation. Smooth muscle bridged the defect within 5 weeks and the margins of the muscularis were thickened and cellular in early stages; cells were elongated and extended towards the defect from the muscular remnant. Primitive smooth muscle cells were present at defect margins. This evidence indicates that smooth muscle was replaced by hyperplasia.

Animals↗

Epithelialization after cystotomy.

Cystotomies were performed on mature guinea pigs using aseptic technique, and one layer closure with polypropylene sutures. It was found that epithelialization over the suture material was completed by 3 days and that epithelialization of the bladder mucosa itself after a mucosa-mucosa approximation was completed within 4 days. The main significance of this investigation is that the normal bladder mucosa was completely healed within 4 days.

Animals↗

Retreatment of recurrent pelvic tumors with iodine-125.

We describe our experience with successful retreatment of common pelvic tumors including recurrent cervical and endometrial cancer, colorectal cancer, and soft tissue sarcomas. Two different permanent interstitial 125iodine (125I) endocurietherapy (ECT) techniques were employed. The first technique, percutaneous transperineal template 125I ECT, was used in the retreatment of recurrent tumors located within the true pelvis. The second technique, implantation of 125I in Vicryl carrier following celiotomy, was used for retreatment of recurrent tumors located outside the true pelvis within the false pelvis.

Adult↗

Fluoroscopy guided transperineal percutaneous permanent 125iodine implantation of prostate cancer.

The transperineal percutaneous template permanent iodine interstitial brachytherapy under "C-arm" fluoroscopic guidance is a simple, easily-learned, accurate and rapid procedure which can be performed without subjecting the patient to celiotomy. We have treated 58 patients by the transperineal percutaneous permanent interstitial brachytherapy. The use of transperineal percutaneous technique with C-arm fluoroscopic guidance improves the symmetry and dosimetry of the implant. This results in reduction of the incidence of chronic radiation-induced complications. In the group of 22 patients who underwent brachytherapy without celiotomy and lymphadenectomy and without adjuvant external-beam radiotherapy, there were no major complications.

Brachytherapy↗