TACHYPHYLAXIS. III. EPHEDRINE.
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Animals↗
Biomedical subjects
F F COWAN
Publications and source records attributed to F F COWAN.
Tachyphylaxis. General considerations of the phenomenon.
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Drug Tolerance↗
Catecholamines as possible stimulants of chemoreceptor mechanisms.
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Acetylcholine↗
Reversal of phenylalkylamine tachyphylaxis by norepinephrine.
Since the responses to "neurosympathomimetic amines" are reduced in the reserpinized animal and restored by norepinephrine administration, it was postulated that norepinephrine might also affect the development of their tachyphylaxis. We found that norepinephrine infusion restored, at least partially, certain tachyphylactic responses to amphetamine or ephedrine and fully prevented the development of tachyphylaxis to tyramine.
Amines↗
Explanation of cocaine desensitization of blood pressure responses to ephedrine.
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Blood Pressure↗
Tachyphylaxis of some sympathomimetic amines. A preliminary report.
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Amphetamine↗
The influence of dichloroisoproterenol on isoproterenol vasomotor reversal.
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Blood Pressure↗
Relationship of structure to activity of antihistamines.
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Anti-Allergic Agents↗