PubMed Health⌕ Search

Biomedical subjects

F F Nally

Publications and source records attributed to F F Nally.

At least 19 recordsLinked to original sources
PubMed1988

Oral cancer.

Explore the source record for details and available documents.

Humans↗
PubMed1988

Oral medicine.

Explore the source record for details and available documents.

Dentistry↗
PubMed1986

Cryotherapy in the management of paroxysmal trigeminal neuralgia. Four year follow up of 39 patients.

Paroxysmal trigeminal neuralgia still remains a difficult condition to treat. Carbamazepine (Tegretol) has been a first line treatment, failing this surgery becomes necessary. However, many surgical procedures result in permanent sensory loss. Peripheral cryotherapy, along with the recently described Jannetta (1976) and Hakanson (1981) techniques, attempt to preserve sensation. Cryotherapy to 53 branches of the trigeminal nerve in 39 patients, who were followed up for 4 years, resulted in pain relief out-lasting return of sensation. These cases show that cryotherapy applied to the correctly located affected nerve branches can produce results which are unobtainable by other methods of pain control in paroxysmal trigeminal neuralgia.

Adolescent↗
PubMed1984

A 22-year study of paroxysmal trigeminal neuralgia in 211 patients with a 3-year appraisal of the role of cryotherapy.

The scope of this investigation included a comparative study of 211 patients with paroxysmal trigeminal neuralgia (PTN) seen over 22 years (from 1959 to 1981) and the use of an open-nerve freezing technique (cryotherapy) on peripheral branches of the trigeminal nerve in 42 of these patients over 3 years (from 1978 to 1981). The study was divided into three parts. Part I was an analysis of clinical findings in all patients. Part II dealt with 33 medically uncontrolled patients and was an assessment of cryotherapy under the most adverse conditions. Part III consisted of an unselected group of 16 patients whose pain could be controlled by chemotherapy but who were not in remission. It was an assessment of cryotherapy in 9 of them as a replacement or adjuvant to chemotherapy. A total of 62 operations were performed, resulting in immediate pain relief and the gradual return of sensation in the treated nerve in all patients. The procedure had to be repeated in 6 patients early in the study to achieve this; one probable reason was inadequate freezing. The longest period of relief has been 2 1/2 years so far; the first patient treated 3 years ago, failed to return and could not be traced. Migration of pain to smaller branches of the trigeminal nerve occurred in 16 patients from 3 to 9 months postoperatively. This was abolished by further cryotherapy in the areas of migration. It is postulated that cryotherapy acts both peripherally and centrally to produce pain relief; if the technique is correctly carried out, the results can be long lasting and may be permanent.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1977

Benign mucous membrane pemphigoid (cicatricial mucosal pemphigoid): a reconsideration.

The name cicatricial mucosal pemphigoid is suggested in an attempt to clarify several synonymous terms and to omit the prefix "benign." The clinical features are reviewed and seven case reports illustrating different aspects are presented. The severe effects of ocular and pharyngeal involvement are highlighted, immunologic findings and treatment are discussed, and the link with neoplasia is emphasized.

Aged↗
PubMed1977

Oral non-dystrophic bullous eruption mainly limited to the gingivae: a mechano bullous response. A variant of cicatricial mucous membrane pemphigoid?

Fourteen patients with recurrent blistering entirely restricted to the mouth have been observed for up to 7 years. Their average age was 52 years, and there was a predilection for females (ratio 2-5:1). Patients presented with thick-roofed blisters and denuded, red, boggy areas of mucosa. The area of maximal involvement with the labial gingiva, and whilst the blisters would arise spontaneously, mechanical trauma was the obvious provocative factor in all patients. Gentle friction on normal looking mucosa would produce a bulla which became blood filled. Re-epithelialization usually occurred within 1-3 weeks, with no scarring. Biopsies showed subepithelial bullae, and direct immunofluorescence was positive in the basement membrane zone of 2 of the 5 cases examined. The most striking feature was the extreme fragility of the epithelial attachment to the underlying corium, as shown by a useful clinical test with a probe. In 10 patients, the condition gradually remitted and the probe test became difficult to perform. The term acquired oral non-dystrophic epidermolysis bullosa was considered for the diagnosis, although a forme fruste of cicatricial mucous membrane pemphigoid remained an alternative.

Adult↗
PubMed1976

Adverse reactions to carbamazepine (tegretol).

A review of the literature on adverse reactions to carbamazepine used in treatment of paroxysmal trigeminal neuralgia is presented and a survey of 120 cases is reported. The case reports were selected to emphasise some of the adverse reactions to carbamazepine. The blood picture was monitored every month while patients were on carbamazepine therapy. As with any medication, side-effects and complications may occur. When a patient shows a minor intolerance to the drug, the dose should be reduced to the one that controls the symptoms incompletely but produces no adverse effects. As the patient acquires greater tolerance the dosage may be gradually increased. Periodic monitoring of the blood picture and of liver and kidney function is important.

Aged↗
PubMed1976

Erythema multiforme. Review of twenty-six cases.

A survey of twenty-six cases of erythema multiforme was undertaken. All patients had oral lesions and seventeen had skin involvement, mainly on the hands. The average age was 32 years, and female patients predominated in the group. Nearly one third gave a history of a severe emotional disturbance prior to the attack, four patients developed lesions after penicillin therapy, and two presented initially with acute primary herpes simples stomatitis. Skin and mucosal biopsies were undertaken in some patients, and it was concluded that no pathognomonic features were identifiable; a subepithelial bulla, however, could occasionally help in the differential diagnosis. Other laboratory investigations, including a complete blood count, determination of herpesimplex titer, and urinalysis, were not helpful, except that the erythrocyte sedimentation rate was raised in sever cases. Possible etiologic factors were discussed in relation to the survey. It was thought that the cause is still obescure except in drug-induced cases and that the diagnosis is essentially a clinical one, since various laboratory investigations cannot be shown to produce consistent pathognomonic findings.

Adolescent↗