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Biomedical subjects

F F Tetenev

Publications and source records attributed to F F Tetenev.

16 recordsLinked to original sources

[Significance of the pleura in respiratory mechanics].

The spirogram and transpulmonary pressure curve have been registered, the work of breathing and its subdivisions, pulmonary compliance have been measured in 14 rabbits under intravenous thiopental anesthesia (1st stage). 60 minutes after death the dead bodies have been placed in the box with the pressure, imitating the breathing movements (2nd stage). The isolated lungs have been placed into the Donders beel (3rd stage). The specific work of breathing and active nonelastic part of total work of breathing have been increased during the 2nd stage. The work of breathing and all its subdivisions were significantly increased in the 3rd stage of experiment. Pulmonary compliance was invariable. The whole pleural cavity provided decrease of mechanical work of breathing.

Animals

[Bronchial asthma in a hyperendemic focus of opisthorchiasis (western Siberia)].

The data obtained on bronchial asthma (BA) occurrence in the hyperendemic opisthorchiasis focus in the western Siberia show BA in it to run a more severe and prognostically unfavourable course against the population from other Siberian regions safer by opisthorchiasis. The latter adapted to hepatobiliary system negatively affects the bronchi and lungs due to the involvement of eosinophilic and immunocomplex mechanisms damaging BA patients' shock organ. By means of additional antigenic stimulus, opisthorchiasis sensitization changes BA clinical manifestations and immunological manifestations status of BA patients dictating the necessity of immunological correction. High BA incidence was registered among subjects who had come from areas where opisthorchiasis was encountered less frequently.

Adult

[Pathophysiological classification of external respiratory failure].

On the basis of literature analysis and clinical experience, a classification of external respiratory failure (ERF) is suggested. The types of ERF can be as follows: 1) pulmonary ventilation failure; 2) gas diffusion failure; 3) pulmonary blood flow failure; 4) respiration control failure; and 5) ambient air gas composition change. The forms of ERI can be classified as acute, subacute and chronic. The stages of ERF include the following: I (compensatory) with pulmonary ventilation function drop of degree I-III (of an obstructive, restrictive and mixed type) and without hypoxemia, normo- or hypocapnia; II (subcompensatory) with the same pulmonary ventilation failures, moderate or serious hypoxemia, normo- or hypocapnia; III (decompensatory) with hypoxemia and hypercapnia or extremely severe hypoxemia in combination with normo- or hypocapnia.

Humans

[The effect of the inhalation of a single atrovent dose on pulmonary ventilation function and respiratory mechanics in patients with chronic obstructive bronchitis].

A study was made of the action of inhalation of a single atrovent dose in 20 patients with chronic obstructive bronchitis. All the patients demonstrated a considerable abatement or disappearance of dyspnea, and a reduction of the number of dry rales. The vital capacity of the lungs, the volume of forced expiration, maximal pulmonary ventilation, MOCmax, MOC50, and MOC75 substantially increased. The respiratory work diminished on the average by 32.3% primarily due to the lessening of non-elastic lung resistance. The rise of pulmonary static extensibility and reduction of pulmonary elastic propulsion were recorded. In patients with and without clinical signs of bronchospasm, the action of atrovent was identical.

Administration, Inhalation

[Deformation of the transpulmonary pressure plateau in experimental pulmonary emphysema].

Deformation of the transpulmonary pressure plateau occurring during the interruption of air flow for 0.5 s is described in 8 healthy rabbits and in 9 animals with experimental emphysema induced by the intravenous injection of licopodium spores. The greatest plateau deformity was seen in healthy animals during inspiration, averaging 20 cm H2O. In sick rabbits the degree of deformity was decreased by 13 cm H2O on the average. The plateau deformity was the same in expiration in healthy and sick animals, averaging 7 cm H2O. The direction of changes in the strain of respiratory muscles in response to inspiration or expiration during the air flow interruption was controlled by recording the pressure in the bronchus, whose amplitude of respiratory variations considerably exceeded such of transpulmonary pressure. Inspiratory plateau deformity is regarded to be the result of active sucking action of the lungs, and expiratory plateau deformity--as their active contraction under conditions of the air flow interruption.

Animals

[Bronchial wedge pressure in experimental pulmonary emphysema].

The work of breathing and its subdivisions, pulmonary compliance, the bronchial wedge pressure, intrapleural and esophageal pressures were measured in 8 normal rabbits and in 15 rabbits with emphysema induced by intravenous injections of licopodium spores. Investigations were carried out under intravenous thiopenthal anesthesia. In normal rabbits the amplitude of the bronchial wedge pressure was on the average twice as great as the pleural and esophageal pressures.

Animals