PubMed Health⌕ Search

Biomedical subjects

F Farina

Publications and source records attributed to F Farina.

At least 55 records · Page 3Linked to original sources
PubMed1987

Metabolic alterations induced by hypoxia in the tortoise heart. Comparison between spongy and compact myocardium.

Experiments were performed to check the tolerance to severe hypoxia of the tissue layers (compact and spongy) of the tortoise heart. The animals were subjected to hypoxia (7% O2) at 18 degrees C, 28 degrees C and 38 degrees C for 30, 6 and 2 hr respectively, or to anoxia for 30 hr at 18 degrees C and 2 hr at 38 degrees C. At 18 degrees C the metabolic alterations caused by a 30 hr hypoxia were mild whereas at 28 degrees C and 38 degrees C the cardiac glycogen was depleted, lactate had accumulated and the phosphate creatine and ATP content had decreased. The extent of these metabolic changes was similar in the compact and in the spongy layers of the heart.

Adenosine Triphosphate↗
PubMed1986

[Study of hypophyseal and gonadal hormones and cases of postmenopausal occurrence of bronchial asthma].

A study was conducted into the hormone profile of women with no previous history of allergy who developed bronchial asthma after menopause in order to discover any differences between these and patients of a similar age with allergic bronchial asthma. The serum levels of the following hypophyseal and gonadal hormones were therefore analysed: luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), 17 oestradiol (17BE2) in both groups of patients and in a control group of healthy postmenopausal volunteers. The results showed lower FSH and LH and higher 17B7(2) levels in the patients with bronchial asthma but no clinical history of allergy than in either the patients with allergic asthma or the healthy volunteers. When the hormone picture in some of the group 1 patients normalised, the clinical symptoms disappeared. One possible explanation is the following: excess oestrogen in the "non-allergy" patients might have caused an imbalance in the PgF/PgE ratio which is thought to contribute to the regulation of bronchomotor tone. The same phenomena might also have accelerated the release of arachidonic acid and its metabolites.

Age Factors↗
PubMed1983

Micromethod for determination of lactate dehydrogenase isoenzyme C4 activity in human seminal plasma.

We have developed an automated enzymatic assay for LDH-C4, a lactate dehydrogenase (EC 1.1.1.27) isoenzyme found exclusively in spermatozoa, as a marker of human spermatogenesis. LDH-C4 activity is assayed bichromatically in the Abbott ABA-100 spectrophotometer, with 2-oxohexanoate as substrate. As many as 27 samples (2.5 microL) of human seminal plasma can be analyzed sequentially, with apparent zero-order kinetic conditions and with a precision (CV) of 5%. The apparent Km for the 2-oxohexanoate reaction is 11.2 mmol/L. Electrophoretic and enzymatic studies indicate that LDH-C4 acts on this substrate to produce hydroxyhexanoate, in contrast to lactate dehydrogenase isoenzymes 1 and 5--further evidence for the uniqueness of LDH-C4. The sensitivity, specificity, and speed of this assay system makes it practicable for studies on, and evaluation of, male fertility.

Caproates↗
PubMed1982

[Radiological and telethermographic diagnosis of breast lymphomas (28 cases)].

Twenty eight patients with histologically proven primary or secondary malignant lymphoma of the breast were evaluated by mammography and telethermography between 1968 and 1980 at Istituto Nazionale Tumori of Milan. This histological type is rather unusual and poor is the radiological literature on the matter. The roentgenographic findings showed especially isolate nodes with clear-cut or irregular outline, multiple displasic lesions or diffuse inflammatory-like disease. Because of such a variety of radiological matters, diagnosis is often uncertain. No significant difference between primary or metastatic disease was seen in radiological patterns of non-Hodgkin lymphomas. In the three cases of Hodgkin's lymphoma radiological findings suggested inflammatory disease. Telethermography was usefully associated showing, in the majority of cases, high hyperthermia also in "benign" mammographic patterns.

Adult↗