[Changes in brain levels of taurine and glutamate induced by cortical perfusion with taurine].
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Biomedical subjects
Publications and source records attributed to F Fassio.
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The possible preventive action of taurine administered through a cortical perfusion, has been studied in bilateral and simmetrical foci with bisynchronous discharge. The data obtained showed that: 1)taurine preventive action is less remarkable in bilateral and simmetrical foci; 2) when administered trough the appropriate route, taurine always has a preventive antiepileptic effect. Our data, compared to those of Marcus e al., confirme that bisynchronous discharge, resistant to taurine preventive and terapeutic action, is the obligatory expression of interactions of bilateral and simmetrical foci.
In a patient with atypical bilateral internuclear ophthalmoplegia the optokynetic test and the ocular dysmetria test detected an infraclinical bilateral lag of adduction. The optokinetic test showed amplitude asymmetry of nystagmus, which was larger in both eyes when the fast phase was in abduction. The ocular dysmetria test showed in both eyes that saccades were slower in adducting than abducting saccades: the latters overshooted and showed transient nystagmus. Since bilateral internuclear ophthalmoplegia is often indicative of multiple sclerosis, these tests are particularly helpful in those patients who otherwise would require more complex diagnostic investigations.