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Biomedical subjects

F Fischl

Publications and source records attributed to F Fischl.

43 records · Page 3Linked to original sources

[Newborn of more than 4000 grams birthweight (author's transl)].

Perinatal morbidity and mortality are well known to be higher in macrosomatic neonates, whose birthweight is 4000 g or more. 398 mothers of such macrosomatic infants and 7314 mothers of infants of normal weight were retrospectively reviewed for factors possibly influencing fetal weight. The following items were found to be statistically more frequent or predominant in the study group than in the controls: preconceptional obesity, weight gain of more than 20% during pregnancy, multiparae with an history of macrosomatic infants. Gestation-diabetes (prediabetes) and a family history of diabetes mellitus were observed rarely and did not seem to be of great significance.

Birth Weight↗

[Treatment of hypotension complicating pregnancy improves fetal outcome].

A prospective study 30 out of 60 pregnant women suffering from pathologic hypotension were treated regularly with the mineralocorticoid 11-Desoxycorticosteronönanthat (Cortiron (R)-Depot). To the other 30 women no medication was given --they served as a control-group. In order to get information on the uteroplacental perfusion rate, placental flow measurements using radioisotopes were carried out. In comparison with the untreated blood-pressure and placental perfusion in the medicated pregnant women was significantly higher. The investigation of the fetal outcome showed 600 g heavier neonates in the mineralocorticoid treated group; the rate of dystrophy was significantly lower. The results entitle the requirement of medication in cases of maternal hypotension (RR 110/65 mm Hg and below). By our experiences we can recommend the mineralocorticoid Cortiron (R)-Depot.

Adult↗

[Juvenile metrorrhagia by Willebrand Jürgens syndrome (author's transl)].

Juvenile bleeding is a symptom frequently observed in a children's gynecologic outpatient clinic. In rare cases this symptom does not represent a disturbance of hormonal regulation systems, but may be due to a coagulopathy. We represent a patient of an age of 12 years, who was admitted with the diagnosis: juvenile metrorrhagia. The final diagnosis: Willebrand-Jürgens syndrome would be established after invasive examinations and a series of blood tests. The presentation of this case suggests to consider coagulopathies as a cause of bleeding in similar cases. The special condition should be tested in cooperation with hematologists.

Blood Coagulation Factors↗

[Clinical experiences of continuous pH measurements on the fetus during delivery (author's transl)].

Under clinical observation 22 continuous measurements of tissue pH were carried out according to Stamm's method, causing a number of questions, such as usability, possible faults and susceptibility to trouble. Testing the accuracy of measurements was a decisive factor, i.e. conformity of blood pH (determined intermittently according to the conventional method) with tissue pH was tested according to the new method. Furthermore, these values were compared to gas analytical findings in artery and vein of the umbilical cord of the new borns.

Blood Gas Analysis↗

[pH measurements following delivery from breech presentation (author's transl)].

In 1977 the adaptation capability of 22 out of 89 breech presentation new-borns was studied by way of punctual pH-measurements within the first 30 minutes after birth. Thus, it was possible to gain an insight into the extra-uterine adaptation, especially with respect to the mode of delivery. Further points of comparison were parity, maturity and a possible correlation with the Apgar Score. The study included a comparison with identical measurements of 20 spontaneous head position new-borns. According to the results under certain preconditions a vaginal delivery in breech presentation is also today by all means to be justified.

Adaptation, Physiological↗

[Antepartum and intrapartum cardiotocographic changes in pregnant women with diabetes mellitus].

In 69 insulin-dependent diabetic patients antepartal as well as intrapartal CTG's were evaluated retrospectively according to Fischer and Hammacher scores, revealing a marked decrease or a lack of decelerations together with a limitation of the oscillation amplitudes in the antepartal CTG. These show a marked increase during the last weeks of pregnancy. Intrapartal decelerations similar to variable dips are far more frequent. The same alterations, though less marked, are in part also found in latent diabetics. Owing to the small number of patients, and to a lack of literature in this field, no definitive conclusion can be drawn yet. Thus, prospective studies will still have to be carried out on a larger scale.

Female↗