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F Flocard

Publications and source records attributed to F Flocard.

41 records · Page 3Linked to original sources
PubMedDate not supplied

[Diagnosis of muscular intolerance during exercise caused by enzyme deficiency in adults].

The exertional muscle pain syndrome in adults is expressed by recurrent episodes of pain and/or episodes of acute rhabdomyolysis, sometimes with transient myoglobinuria or even acute renal failure. The enzymatic origin of this syndrome is suggested by a familial history, by its usual onset during childhood or adolescence, and by its recurrent attacks usually, but not exclusively, caused by exercise. The aetiological diagnosis, suggested by the clinical context and some dynamic tests, is almost always based on good histological and biochemical examinations of the muscle biopsy.

Adult↗
PubMedDate not supplied

[Mitochondrial cytopathies].

Mitochondrial cytopathies are diseases due to a defect of mitochondrial respiratory chain and are characterized by the presence of morphological abnormalities of mitochondria (ragged red fibers). The clinical manifestations can be polymorphic as various organs may be involved; but in general, these disorders affect either muscle alone (progressive external ophtalmoplegia, myopathy with weakness) or muscle and brain (encephalomyopathies). Some of these diseases may be due to alterations of the mitochondrial genome. Diagnosis can be achieved through the following steps: measurement of lactate, pyruvate and ketone bodies after fasting followed by a carbohydrate rich meal and/or exercise; histological examination and biochemical investigation of a skeletal muscle biopsy; study of possible mitochondrial genome alterations.

Humans↗
PubMedDate not supplied

[Upper digestive system endoscopy in Gabon. Contribution of 2 years' experience].

Reporting on 805 endoscopies of upper digestive tract performed in a rural area of Gaboon during a period of 28 months, the authors describe the indications and the results by analysing comparatively their findings with some other African ones. Their experience is deeply in favour of performing much more often fibreoptic endoscopy, even if the percentage of investigations revealing no anomaly is high, because its indisputable medical and economical interest.

Adolescent↗
PubMedDate not supplied

[Three successive cases of salmonella meningitis in Gabon].

In a two months period Salmonella ajiobo and S. typhimurium (twice) were isolated from cloudy cerebrospinal fluids (CSF) of children less than one year old. No other cases of Salmonella meningitis occurred in a 2 year survey of meningitis in Franceville, a semi-rural community in southeastern Gabon. One case was fatal and the case with S. ajiobo needed a prolonged course since the CSF was not sterilized even after 6 days of therapy.

Female↗