Conjoint versus one-person family therapy: further evidence for the effectiveness of conducting family therapy through one person with drug-abusing adolescents.
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Adolescent↗
Biomedical subjects
F Foote
Publications and source records attributed to F Foote.
Proconvulsant effect of morphine on seizures induced by pentylenetetrazol in the rat.
The chemoconvulsant pentylenetetrazol (PTZ) was administered by a variety of routes to rats pretreated with morphine (10-50 mg/kg s.c.). In a naloxone-reversible, dose-dependent manner, morphine decreased the threshold for seizures induced by the slow intravenous infusion of PTZ. In addition, morphine increased the severity of seizures induced by the intravenous, intraperitoneal, and subcutaneous routes of administration of PTZ. Morphine also caused an increased incidence of multiple seizures following subcutaneous administration of PTZ. These results demonstrate that morphine has a proconvulsant effect on PTZ-induced seizures in the rat.
Animals↗
Morphine potentiates seizures induced by GABA antagonists and attenuates seizures induced by electroshock in the rat.
In a naloxone-reversible, dose-dependent manner, morphine (10-50 mg/kg i.p.) protected against seizures induced by maximal electroshock and increased the incidence and severity of seizures induced by bicuculline, in rats. Morphine also potentiated seizures induced by isoniazid and by picrotoxin. Thus, opiate activity influences the expression of seizures in contrasting ways depending upon the mode of seizure induction. Since morphine consistently potentiated seizures induced by interference with GABA transmission, it appears that GABAergic systems may be of particular significance for the elucidation of the varied effects of morphine on seizure susceptibility.
Animals↗
The origins of fear of snakes.
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Animals↗
Prospectively gated cardiac computed tomography.
A fourth-generation scanner has been modified to perform prospectively gated cardiac computed tomography (CT). A computer program monitors the electrocardiogram (ECG) and predicts when to initiate the next scan in a gated series in order to acquire all projection data for a desired phase of the heart cycle. The system has been tested with dogs and has produced cross-sectional images of all phases of the cardiac cycle. Eight to ten scans per series were sufficient to obtain reproducible images of each transverse section in the end-diastolic and end-systolic phases. The radiation dose to the skin was approximately 1.4 cGy per scan. The prospectively gated system is more than twice as efficient as a retrospectively gated system in obtaining complete angular projection data for a 10% heart cycle window. A temporal smoothing technique to suppress reconstruction artifacts due to sorting inconsistent projection data was developed and evaluated. Image noise was reduced by averaging together any overlapping projection data. Prospectively gated cardiac CT has also been used to demonstrate that the error in attenuation measured with a single nongated CT scan through the heart can be as large as 50-60 CT numbers outside the heart in the lung field.
Animals↗