[Deterministic differential equations in cytokinetics].
Carcinogenesis is generally viewed as the result of a disrupted equilibrium between the processes of proliferation, differentiation, migration and loss. In cell kinetics, perturbation of fundamental kinetic parameters such as the mitotic index or the growth fraction may reflect a carcinogenic process. In this paper, we present a system of deterministic differential equations describing the dynamical evolution of a cell population. We show that this model can account for asynchronicity of cells and simulate the fraction of labelled mitoses experiment as well.
Cell Cycle↗