PubMed Health⌕ Search

Biomedical subjects

F Franchini

Publications and source records attributed to F Franchini.

At least 19 recordsLinked to original sources
PubMed2001

Enhancing implant surgery planning via computerized image processing.

Computerized tomography (CT) and magnetic resolution imaging (MRI) are the medical imaging modalities to deliver cross-sectional images of the human body. In the last decade, CT has become the most frequently used imaging modality for the evaluation of the jaw for dental implants. Furthermore, image reformatting software has been developed in order to obtain a correct preoperative diagnosis and treatment planning regarding osseointegrated implants. Previous work has shown that CT images are affected by a distortion ration from 0% to 6%. This might be due to the alignment of the patient during scanning, to his/her movements, or possibly to the saturation of pixels composing the image. In order to solve the former problem, intraoral stents can be used to center the patient's head perpendicular to the axis of the implant to be inserted. However, if more than one implant must be placed - possibly with very different axes - it would be necessary to acquire the corresponding number of tomograms, each perpendicular to the axis of one planned tooth. Obviously, it would be better not to expose the patient to multiple CT scanning. In this work, we present a software approach for enhancing implants surgery planning in order to obtain exact morphological measurements of the bone and planned teeth with a single CT acquisition. This is achieved by applying image-processing techniques to the original CT images, in order to produce new Ct images lying on different planes, and possibly perpendicular to a different tooth. The resulting software system (Dental/Vox) has been implemented in C+ + and runs on Intel-based personal computers under the Windows operating systems. DentalVox ensures better mechanical results in the design and planning of a dental implant compared to other, similar software tools; it can reconstruct axial (and panorex and cross-sectional) images once any direction is chosen. This makes it possible to implant a mechanically and esthetically superior prothesis in the underlying gnathic morphology.

Dental Implantation, Endosseous↗
PubMed2000

Is the 13C-acetate breath test a valid procedure to analyse gastric emptying in children?

BACKGROUND/PURPOSE: Scintigraphy is regarded as the "gold standard" procedure in measuring gastric emptying (GE) rates. 13C-acetate breath test (ABT), which already has been validated in adults, is a noninvasive and nonradioactive alternative method. The aim of the current study was to validate ABT against technetium Tc 99m scintigraphy in children affected by delayed GE. METHODS: Sixty children were recruited and divided into 2 groups: group A, 30 healthy controls; group B, 30 patients with gastroesophageal reflux, and scintigraphy-documented DGE (15 neurologically impaired). After an overnight fast, all of them underwent ABT using 25 to 150 mg 13C-acetate. Breath samples were obtained at baseline and then every 10 minutes for 2 hours. The 13CO2 to 12CO2 ratio in breath samples was analysed by isotope ratio mass spectrometry. Data are expressed as follows: time of peak 13C exhalation (tP13CO2b) and half emptying time in ABT (t(1/2b)), and scintigraphy half emptying time (t(1/2s)). RESULTS: In controls tP13CO2b was 37 +/- 13 minutes and t(1/2b) 74 +/- 12 minutes. In patients tP13CO2b and t(1/2b) were, respectively, 65 +/- 26 minutes and 104 +/- 18 minutes t(1/2s) was 91 +/- 21 minutes. In group B tP13CO2b and t(1/2b) were delayed significantly compared with controls, respectively, P < .03 and P < .01. In group B significant correlation between t(1/2s) and t(1/2b) was noted (r1 = 0.97). A close correlation was also observed between t(1/2s) and tP13CO2b (r2 = 0.95). CONCLUSION: The 13C ABT is an easy, reliable, and less expensive procedure for measuring GE, and its results closely correlate with those of scintigraphy in a paediatric population.

Acetates↗
PubMed1988

Plasma infusion for hemolytic-uremic syndrome in children: results of a multicenter controlled trial.

The results of a controlled trial to ascertain the usefulness of plasma infusion for the treatment of hemolytic-uremic syndrome (HUS) are reported. Criteria for admission were (1) observation within 8 days from first symptoms, (2) dialysis treatment required, and (3) no special treatments and no more than 25 ml blood/kg previously received. Children were subdivided according to age (less than or more than 3 years) and then randomly assigned to treatment with plasma or symptomatic therapy. Thirty-two children ranging in age from 4 months to 6 years entered this study; 17 received plasma (P+ group) and 15 only symptomatic therapy (P- group). The mean follow-up period was 16 months in both groups. Surgical renal biopsy was performed 29 to 49 days after onset in 11 P+ and 11 P- children, and 33 histologic findings were semiquantitatively evaluated. No death occurred in either group. No differences were found in blood pressure, proteinuria, or hematuria at the end of the follow-up period; in no case were severe arteriolar lesions found. There were no significant differences for the scores of the individual histologic measurements; on electron microscopy, no vascular changes were observed in seven children of the P+ group, whereas in five of seven of the P- group, thickening of the lamina rara interna and arteriolar damage were present. The ability of plasma to stimulate prostacyclin (PGI2) production, measured as its stable derivative 6-keto-PGF1 alpha, was within the normal range for all patients. In our patients with predominant glomerular involvement who were treated in a very early phase of HUS, infusions of plasma did not significantly influence the short- and medium-term clinical outcome and were not effective in severe HUS when given later in the course of the disease. A longer follow-up is needed to ascertain whether the presence of endothelial damage, demonstrated by electron microscopy in children who were not given plasma, is of clinical relevance.

Biopsy↗
PubMed1981

Diagnostic value of objective campimetry.

The results obtained in ten normal subjects with a new method of pupillocampimetry are described and compared with those obtained with routine campimetry. Once the relationship between the two methods was established, ten subjects suffering from pregeniculate or postgeniculate lesions of the optic pathways were examined by pupillocampimetry. This study shows the value of this new method, particularly for the differential diagnosis of pre- or postgeniculate lesions.

Adaptation, Ocular↗