[Citrate metabolism. 3. Curves of intravenous tolerance tests in premature and full-term newborn infants].
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Biomedical subjects
Publications and source records attributed to F Franchini.
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In the last five years, in the Surgery Pediatric Department and in the Pediatric Nephrology and Dialysis Service of the Florence University, have been observed 13 patients with cystic renal diseases. In every single case, for the diagnosis we have considered the age of the patients and the examinations made to them. We payed attention mostly to the echography considered the main diagnostic examination, even in prenatal age.
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The clinical, radiological and anatomo-evolutive pictures of this syndrome are typical. It is suggested that cases are more frequent than is generally thought and that their recognition is delayed on account of the considerable time that often elapses before repeated infection of the respiratory system, particularly the middle lobe, results in the onset of the syndrome.
Adolescent had in the past rarely been affected by sexually transmitted infections. Nowadays they must be considered possibly running such risks as they begin their sexual activity earlier or do not know enough about these kinds of troubles. Therefore a valid primary prevention is necessary based upon correct information.
It is by now clear that pediatrician's interest about adolescent's matters is very much increasing. The Authors take into consideration vulvovaginitis, a particular matter which is very frequent during this period of life and describe its most important clinical aspects.
The clinical and radiological characteristics of idiopathic scoliosis with onset in the first year of life is described. The importance of a careful objective examination of nurslings with respect to scoliosis is stressed.
During these past years pediatricians have been more and more interested to the adolescent's matters. Undoubtedly adolescent's behavioural disturbances are to be bound to a childhood spent in a wrong way, and contemporarily managed by parents who, despite their maximum dedication, have not "trained" their children according to specific "fundamentals", probably because also they themselves, when children, have not been submitted to them.
Feeding children involves a mutual interaction between their parents and them; interaction in which everyone is influenced by and, contemporarily, influences the others. In fact the act of administering food is considered to be fundamental inside the relationship between the mother and her child. Such a relationship can supply consequences that are important for the children's physical, emotional and cognitive growth, particularly in their first two years of life. Therefore, any time a child arrives at the pediatrician's attention showing a nourishment matter, and anamnesis and examination are indicative of a lack of evidence that may address to a physical disease, the next zone to be indagated must be the existing relationship between the child and his family.
The authors review the origins and the metabolism of omega-6 and omega-3 fatty acids and particularly consider the implications of desaturase's deficiency and of the usual imbalanced supply of fatty acids in the diet of children. The peculiarity of the fatty acids is to be, while proteins express the genome, the expression of the diet on the cell's membranes, with a subtle influence of an enzyme's equipment varying during the life. All that gains an extraordinary relief, because the omega-6 and omega-3, and constituents of the membranes, are precursors of different series of prostaglandins, which are wholebody mediators of multiple phenomenons like inflammation, immunity, allergy, platelet aggregation, ecc. The authors point how a balanced diet or a supplementation with omega-3, omega-6 and PUFA can help a good development especially of the nervous tissue and of the mucosal barrier. Furthermore modulating the above physiopathological mechanism, also in children could influence recurrent and chronic diseases.
Not very carefully taking into account a possible psychosomatic pathology in children can, in many occasions, cause the pediatrician to make seriously wrong diagnostic, prognostic and therapeutic evaluations. As this is valid at any age, the authors affirm that particularly at the evolutive age, and since the first months of life, many circumstances occur in which the functional trouble can sometimes a serious organic pathology.