[Case of tuberculosis in the buccal mucous membrane].
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Biomedical subjects
Publications and source records attributed to F Fujita.
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This study evaluated the efficacy of a novel hyaluronic acid (HA) gel for preventing adhesions in a rat caecal model. The gel was manufactured from an acidic HA solution using a freezing procedure. HA gel films with four different half-lives (50-200 h) in physiological buffered saline at 37 degrees C were prepared, by regulating the freezing time, and tested. The HA gel film was applied as a barrier on the injured caecal surface after standardized treatment with a rotary abrasion apparatus. A control group of 20 animals were abraded in the same way but not treated. Seven days after the initial operation, the incidence and severity of any adhesions were recorded. Application of the HA gel film significantly reduced the incidence and severity of adhesion formation in all treatment groups compared with the control group. This novel HA gel film is effective for reducing post-operative adhesions in this rat model and the resorption rate is optimum for adhesion prevention on the caecal surface.
A method of estimating subglottal pressure through intraoral pressure has been reported in the literature. In order to determine its clinical usefulness, however, the method should be tested against direct measurements made on subjects with pathologic larynges. The present study was designed to compare intraoral pressure versus subglottal pressure, as measured with a sensing tube inserted through a tracheal stoma. Results showed that intraoral pressure of /i:pi:/ was almost equivalent to subglottal pressure of /i:/ when the latter was smaller than about 25 cmH20. When subglottal pressure exceeded this value, however, the intraoral pressure was smaller than the subglottal pressure. We conclude that the magnitude of subglottal pressure is not invariably identical with intraoral pressure.