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F Funck

Publications and source records attributed to F Funck.

60 records · Page 4Linked to original sources
PubMedDate not supplied

[Proposal for a discriminant level of BNP in very elderly persons with heart failure].

A diagnosis of heart failure (HF) in elderly patient can be difficult. The purpose of this study is to evaluate the cut-off of brain natriuretic peptide (BNP) Triage Assay (Biosite) in the diagnosis of HF in this population : 250 very older patients with age <or= 75 years (mean 82.7 years) were included in this study; 180 patients were diagnosed with HF based on clinical and echocardiographic findings. The sensibility is of 95% at 100 ng/L versus 83% at 300 ng/L. The specificity is of 21% versus 50% at 300 ng/L. The positive predictive value is of 17% at 100 ng/L versus 23% at 300 ng/L. The negative predictive value is of 96% at 100 ng/L versus 95% at 300 pg/L. The cut-off set at 300 ng/L is more suitable as HF marker in the very old population.

Age Factors↗
PubMedDate not supplied

[BNP and dyspnea: proposition of a diagnostic strategy based on two cut-off].

The purpose of this study was to evaluate the cut-off value of brain natriuretic peptide (BNP) assayed with AxSYM BNP assay (Abbott). 86 patients have been included (mean age of 66 years). The clinical sensibility was 100% at 100 ng/L versus 80% at 250 ng/L. The clinical specificity was 66% at 100 ng/L versus 92% at 250 ng/L. The positive predictive value was 80% at 100 ng/L versus 92% at 250 ng/L. The negative predictive value was 100% at 100 ng/L versus 88% at 250 ng/L. The double cut-off strategy is more suitable to diagnose a dyspnea of cardiac origin than the usual strategy based on a single cut-off.value. With such a strategy, the two cut-off strategy improve the diagnosis of 9% in the total population.

Acute Disease↗